Evidence map›Paper›PMID 41601198›Full record

Observational studyJournal of rehabilitation medicine2026

Associations between heart rate and physical activity in people with post-COVID-19 condition accounting for myalgic encephalomyelitis/chronic fatigue syndrome symptoms.

Rachel Adodo, Antonio Sarmento Da Nobrega, Rodrigo Villar, Sandra C Webber, Diana C Sanchez-Ramirez

Abstract readObservational Study
In one paragraph

Observational study in Journal of rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel AdodoDepartment of Respiratory Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, Canada.
Antonio Sarmento Da NobregaDepartment of Respiratory Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, Canada.ORCID 0000-0001-6391-5652
Rodrigo VillarFaculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Canada.ORCID 0000-0001-8568-3346
Sandra C WebberDepartment of Physical Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, Canada.ORCID 0000-0001-7238-4638
Diana C Sanchez-RamirezDepartment of Respiratory Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, Canada. diana.sanchez-ramirez@umanitoba.ca.ORCID 0000-0003-1637-4309

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTachycardia after mild activity or during rest is a common complaint among people with post-COVID-19 condition (PCC). Understanding the relationships between heart rate (HR) and physical activity (PA) in this population is crucial for developing appropriate rehabilitation protocols.

objectiveTo investigate the associations between HR and PA in individuals with PCC, accounting for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) symptoms.

designObservational study. SUBJECTS: Sixteen adults with PCC (81% females, mean age 51 ± 12 years).

methodsParticipants were instructed to use 2 wearable devices (Garmin smartwatch and ActiGraph accelerometer) during waking hours over 4 days while performing daily activities. Average HR, percentage of time in tachycardia (time with HR > 100 bpm), and daily step count were assessed. The accelerometer counts per minute was used to categorize daily PA as sedentary, light intensity, and moderate-to-vigorous (MVPA).

resultsParticipants wore the watches and accelerometers for a mean of 11.36 ± 2.60 and 12.51 ± 1.94 h per day, respectively. Average daily HR increased with increasing PA levels from sedentary to MVPA. However, the percentage of time in tachycardia was significantly lower during periods of MVPA compared with sedentary periods, even after adjusting for ME/CFS symptoms.

conclusionIndividuals with PCC in our study experienced more tachycardia during periods of minimal physical activity compared with periods categorized as MVPA.

Indexed as

COVID-19ExerciseFatigue Syndrome, ChronicHeart RateAccelerometryAdultFemaleHumansMaleMiddle AgedSARS-CoV-2Wearable Electronic Devices

Identifiers

PMID41601198
PMCPMC12856579

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.