Evidence map›Paper›PMID 41600923›Full record

ArticleVaccines2025

Structure-Guided Engineering of Protein VP2 from Epizootic Hemorrhagic Disease Virus Maximizes Production and Confers Complete Protection as Subunit Vaccine.

Samuel Jurado, Luis Jiménez-Cabello, María Del Carmen Nuñez, Sergio Utrilla-Trigo, Eva Calvo-Pinilla, Iván Mazuecos-Aragonés, José Ramón Gutierrez, Ana Falcón, Javier Ortego, José M Escribano

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Samuel JuradoAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.
Luis Jiménez-CabelloCentro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Valdeolmos, 28130 Madrid, Spain.ORCID 0000-0001-8085-5823
María Del Carmen NuñezAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.ORCID 0009-0000-5789-7558
Sergio Utrilla-TrigoCentro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Valdeolmos, 28130 Madrid, Spain.
Eva Calvo-PinillaCentro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Valdeolmos, 28130 Madrid, Spain.ORCID 0000-0002-4667-4081
Iván Mazuecos-AragonésCentro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Valdeolmos, 28130 Madrid, Spain.
José Ramón GutierrezAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.
Ana FalcónAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.
Javier OrtegoCentro de Investigación en Sanidad Animal (CISA), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Valdeolmos, 28130 Madrid, Spain.ORCID 0000-0002-4275-7277
José M EscribanoAlternative Gene Expression S.L. (ALGENEX), Ronda de Poniente 14, 28760 Madrid, Spain.ORCID 0009-0002-0983-9278

Funding

MICIU/AEI PLEC2024-011240Spanish Centro para el Desarrollo Tecnológico y la Innovación (CDTI) MIG20242123
6 · The paper itself

Abstract

Epizootic hemorrhagic disease (EHD) is an important livestock disease caused by Epizootic hemorrhagic disease virus (EHDV). The recent incursion and wide distribution of EHDV in Europe have increased the need for effective vaccine candidates.

Indexed as

baculovirus vectorEpizootic hemorrhagic disease virusinsect pupaeprotein VP2subunit vaccineTrichoplusia ni

Identifiers

PMID41600923
PMCPMC12846072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.