Evidence map›Paper›PMID 41600917›Full record

ArticleVaccines2025

Timeliness and Equity: An Analysis of Measles Herd Immunity in a Regional Area of Australia.

Megan Whitley, Katrina Clark, Michelle Butler, Peter Murray, Hannah Briggs, Sharon Saxby, David N Durrheim

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan WhitleyHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.
Katrina ClarkHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.
Michelle ButlerHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.
Peter MurrayHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.
Hannah BriggsHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.
Sharon SaxbyHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.
David N DurrheimHealth Protection Unit, Hunter New England Local Health District, NSW Health, Wallsend NSW 2287, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlobal declines in immunisation rates and a resurgence in measles pose a threat, even in countries like Australia that have achieved elimination status. National coverage in Australia is measured at static timepoints, so it is unclear at what age children received their vaccines. This may permit the emergence of immunity gaps, leaving children susceptible to measles between those reporting timepoints.

methodsA cross-sectional retrospective analysis was conducted using routinely collected data from the Australian Immunisation Register for children residing in Hunter New England Local Health District (HNELHD), New South Wales, born from 1 January 2015 to 1 June 2019 as a quality improvement initiative. Coverage, age at immunisation, and on-time immunisation were described by demographic, local geographic and age variables. Reverse survival analysis was conducted to determine the timing of achieving 95% MCV2 coverage. To ensure the cultural integrity of the research, an Aboriginal researcher co-led the design, analysis and interpretation of results.

resultsThe analysis included 53,390 children. Measles coverage exceeded the national and international target of 95% MCV2 coverage, with coverage in Aboriginal children surpassing national rates for all children. Pockets of low coverage were identified in several smaller geographic areas and subpopulations. Median age of MCV1 receipt was 375 days (IQR: 369-390 days), and MCV2 was 560 days (IQR: 551-583 days). More recent birth cohorts had earlier immunisation. On-time immunisation rates were high, and most children receiving measles immunisation late were still immunised within six months of the schedule date. The 95% MCV2 coverage threshold was achieved at 1582 days of age.

conclusionsRobust measles immunisation coverage and timeliness were found in HNELHD, Australia. Timeliness data analysis is a useful adjunct to static coverage data in understanding immunisation protection. Improving immunisation data availability, accessibility, and timeliness offers potential to better inform targeted public health activity.

Indexed as

Aboriginalcoverageeliminationequityherd immunityimmunisationmeaslestimeliness

Identifiers

PMID41600917
PMCPMC12846410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.