ArticleViruses2026
HIV-1 Genetic Diversity and Drug Resistance Mutation Profiles in Donetsk, Luhansk and Zaporizhzhia Regions.
Anastasiia Antonova, Anatolii Vinokurov, Daria Kustova, Andrei Pochtovyi, Daria Ogarkova, Anna Kuznetsova, Ruslan Adgamov, Elena Tsyganova, Inna Kulikova, Andrei Plutnitskii and 3 more
Abstract read
In one paragraphArticle in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
13 authors.
Anastasiia AntonovaFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.ORCID 0000-0002-9180-9846 Anatolii VinokurovFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.
Daria KustovaFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.ORCID 0000-0002-8382-275X Andrei PochtovyiFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.ORCID 0000-0003-1107-9351 Daria OgarkovaFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.ORCID 0000-0002-1152-4120 Anna KuznetsovaFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.ORCID 0000-0001-5299-3081 Ruslan AdgamovFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.ORCID 0009-0002-7514-5944 Elena TsyganovaMoscow City Center for AIDS Prevention and Control, 105275 Moscow, Russia.
Inna KulikovaDepartment of Emergency Medical Assistance Organisation and Health Risk Management, Ministry of Health of the Russian Federation, 127994 Moscow, Russia.
Andrei PlutnitskiiFederal Medical Biophysical Center Named After A.I. Burnazyan, 123098 Moscow, Russia.
Aleksandr GintsburgFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.
Vladimir GushchinFederal State Budget Institution "National Research Center for Epidemiology and Microbiology Named After the Honorary Academician N.F. Gamaleya", Ministry of Health of the Russian Federation, 123098 Moscow, Russia.
Aleksei MazusMoscow City Center for AIDS Prevention and Control, 105275 Moscow, Russia.
Funding
The Ministry of Health of the Russian Federation Subsidy for the purpose of organising research to assess the prevalence of resistance to antiretro-viral drugs in patients with HIV infection in certain constituent entities of the Russian Federation, the Agreement No. 056-02-2025-311 (dated 10 March 2025
6 · The paper itselfAbstract
The first major HIV outbreak in the Eastern Europe and Central Asia (EECA) region was registered. Phylogeographic analysis revealed that the main exporters of the virus were Donetsk and Lugansk, from which most migration events occurred, and the predominant genetic variant in Donetsk was subtype A. However, despite a relatively high level of understanding of HIV genetic diversity, data on resistance mutations remain limited. The aim of this study is to assess HIV genetic diversity and drug resistance in Donetsk, Luhansk and Zaporizhzhia regions. A comprehensive examination was conducted, encompassing 392 sequences covering the integrase-coding region of the HIV-1
Indexed as
Drug Resistance, ViralGenetic VariationHIV-1HIV InfectionsMutationAnti-HIV AgentsGenotypeHumansPhylogenyPhylogeographyAnti-HIV Agentsdrug resistance mutationsDTGEECAgenetic diversitygenetic variantsHIV-1RAL
Identifiers
PMID41600908
PMCPMC12846670
What OpenQuestion holds
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LicenceCC BY
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