Evidence map›Paper›PMID 41600851›Full record

ArticleViruses2026

Mpox Clade IIb Virus Introduction into Kinshasa, Democratic Republic of the Congo, July 2025.

Tony Wawina-Bokalanga, Eddy Kinganda-Lusamaki, Christian Ngandu, Prince Akil-Bandali, Jérémie Kundey-Mafu, Nadege Ngombe, Laurens Liesenborghs, Princesse Paku-Tshambu, Lorenzo Subissi, Pauline-Chloé Muswamba-Kayembe and 34 more

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Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

44 authors.

Tony Wawina-BokalangaInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.ORCID 0000-0001-6659-0267
Eddy Kinganda-LusamakiInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.ORCID 0000-0001-9795-0165
Christian NganduInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Prince Akil-BandaliInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Jérémie Kundey-MafuHôpital Général de Référence de Kinkole, Kinshasa P.O. Box 243, Democratic Republic of the Congo.
Nadege NgombeInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.ORCID 0000-0002-2859-7238
Laurens LiesenborghsDepartment of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Princesse Paku-TshambuInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Lorenzo SubissiWorld Health Organization, CH-1211 Geneva, Switzerland.ORCID 0000-0001-5147-575X
Pauline-Chloé Muswamba-KayembeInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Samy Tessi-MvutukuluHôpital Général de Référence de Kinkole, Kinshasa P.O. Box 243, Democratic Republic of the Congo.
Jacques Santini-MafutaHôpital Général de Référence de Kinkole, Kinshasa P.O. Box 243, Democratic Republic of the Congo.
Gradi Luakanda-NdelemoInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.ORCID 0009-0004-0406-2361
Olga Ntumba-TshitengeWorld Health Organization Country Office, Kinshasa P.O. Box 1899, Democratic Republic of the Congo.ORCID 0009-0001-9942-1758
Mory KeitaWorld Health Organization Regional Office for Africa, Brazzaville P.O. Box 06, Congo.ORCID 0000-0002-6304-9288
Israel Cinkobu-BualukenguHôpital Général de Référence de Kinkole, Kinshasa P.O. Box 243, Democratic Republic of the Congo.
Emmanuel Lokilo-LofikoInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Fiston Cikaya-KankolongoInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Sikoti JosaphatInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Cris KacitaInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Adelar LofungolaInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Judith Tete-SitraInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Raphael Lumembe-NumbiInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Elzedek Mabika-BopeInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Adrienne Amuri-AzizaInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.ORCID 0000-0002-5516-0779
Daan JansenDepartment of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.ORCID 0000-0003-4612-6891
Jean-Claude Makangara-CigoloInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.ORCID 0000-0002-1791-2247
Jeanine NkakuluAfrica Centres for Disease Control and Prevention, Addis Ababa P.O. Box 3243, Ethiopia.
Yap BoumAfrica Centres for Disease Control and Prevention, Addis Ababa P.O. Box 3243, Ethiopia.
Ngashi NgongoAfrica Centres for Disease Control and Prevention, Addis Ababa P.O. Box 3243, Ethiopia.
Sofonias TessemaAfrica Centres for Disease Control and Prevention, Addis Ababa P.O. Box 3243, Ethiopia.
Nick LomanInstitute of Microbiology and Infection, University of Birmingham, Birmingham B15 2TT, UK.
Áine O'TooleInstitute of Ecology and Evolution, University of Edinburgh, Edinburgh EH9 3FL, UK.
Anne W RimoinDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA.
Pierre AkilimaliInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Nicole A HoffDepartment of Epidemiology, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, CA 90095, USA.ORCID 0000-0002-1770-6304
Jason KindrachukDepartment of Medical Microbiology & Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.ORCID 0000-0002-3305-7084
Steve Ahuka-MundekeInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Martine PeetersTransVIHMI, Institut National de Santé et de Recherche Médicale (INSERM), Institut de Recherche pour le Développement (IRD), Université de Montpellier, 34090 Montpellier, France.
Dieudonné MwambaInstitut National de Santé Publique (INSP), Kinshasa P.O. Box 3088, Democratic Republic of the Congo.
Koen VercauterenDepartment of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Andrew RambautInstitute of Ecology and Evolution, University of Edinburgh, Edinburgh EH9 3FL, UK.
Jean-Jacques Muyembe-TamfumInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.
Placide Mbala-KingebeniInstitut National de Recherche Biomédicale (INRB), Kinshasa P.O. Box 1197, Democratic Republic of the Congo.

Funding

Emerging Infectious Diseases Research Center - East and Central AfricaU01AI151799 · NIAID · WASHINGTON STATE UNIVERSITY · PI M KARIUKI NJENGA · 2020 to 2026
$10.4M
Agence Française de Développement through the AFROSCREEN project CZZ3209Belgian Directorate-General for Development Cooperation and Humanitarian AidBill & Melinda Gates Foundation INV-018278Canadian Institutes of Health Research; the International Mpox Research Consortium (IMReC) through funding from the Canadian Institutes of Health Research and International Development Research Centre MRR-184813Gates Foundation INV-018278Global Health European and Developing Countries Clinical Trials Partnership 3 (EDCTP3) Joint Undertaking 101195465 - MBOTE-SKInstitute of Tropical Medicine Structurele Onderzoeksfinanciering (Flemish Government; Science, Technology, and Innovation)NIAID NIH HHS U01 AI151799Research Foundation Flanders ("Fonds voor Wetenschappelijk Onderzoek-Vlaanderen" G069725N and G096222NUS Department of Defense Threat Reduction Agency; the US Department for Agriculture Research Service HDTRA1-21-1-0040US NIAID/NIH through Center for Research in Emerging Infectious Disease-East and Central Africa (CREID-ECA) U01AI151799Wellcome TrustWorld Health Organization 001
6 · The paper itself

Abstract

Clade I mpox virus (MPXV) is endemic in the Democratic Republic of the Congo (DRC). Recent studies have described the changing epidemiology of mpox in the country, which has been mainly characterized by the emergence of new MPXV lineages, Clade Ib/sh2023 and Ia/sh2024, associated with sustained human-to-human transmission. Both Clade Ib/sh2023 and Ia/sh2024 are co-circulating in Kinshasa, the capital city of the DRC. Here, we report the first two cases of Clade IIb/sh2017 identified in Kinshasa, DRC, imported from West Africa and locally transmitted. Clinical specimens were collected and tested by PCR. We performed whole genome sequencing using a tiled-amplicon sequencing approach with Clade IIb MPXV-specific primers. The phylogenetic tree shows that Kinshasa Clade IIb MPXV is assigned to Clade IIb/sh2017 within the newly designated lineage G.1, as identified in January 2025 in Sierra-Leone.

Indexed as

Mpox, MonkeypoxOrthopoxvirusAdultDemocratic Republic of the CongoFemaleGenome, ViralHumansMalePhylogenyWhole Genome Sequencingcase investigationsClade IIDemocratic Republic of the CongoDRCgenome sequencingmpoxmpox virusMPXVviruses

Identifiers

PMID41600851
PMCPMC12846488

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.