Evidence map›Paper›PMID 41600745›Full record

ArticleVeterinary sciences2026

Serum Growth Differentiation Factor 8 (Myostatin) Concentrations in Cats with Early-Stage Chronic Kidney Disease.

Kerrigan Fleming, William H Whitehouse

Abstract read
In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kerrigan FlemingDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
William H WhitehouseDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-6080-2684

Funding

Morris Animal Foundation D24FE-608Purdue University West Lafayette N/A
6 · The paper itself

Abstract

Weight loss occurs with chronic kidney disease (CKD) and is present in the early stages. Growth differentiation factor 8 (GDF8), also known as myostatin, is a negative regulator of muscle growth, and circulating GDF8 concentrations are increased in people with CKD. The objective of this study was to evaluate if serum GDF8 concentrations in cats with early CKD are increased compared to healthy cats. Associations of GDF8 with age, sex, body weight, body condition score (BCS), muscle condition score (MCS), and selected renal parameters were also examined. Serum GDF8 in healthy (

Indexed as

cachexiafelinemuscle condition scoresarcopeniaweight loss

Identifiers

PMID41600745
PMCPMC12846599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.