ArticleVeterinary sciences2026
Comparative Study of Cytokine Measurements in Blood Plasma and Serum, and Saliva of Juvenile Pigs During Experimentally Induced Acute Inflammation.
Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Nanoparticulate Immunoactive Complex for Local Chemoimmunotherapy: From Murine Models to Pilot Canine Study.Cancer research communications · 2026Article
- Inflammasome-associated pyroptosis and tumor angiogenesis in prostate cancer.Iranian journal of basic medical sciences · 2026Review
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Authors and funding
4 authors.
Funding
Abstract
This study aimed to assess cytokine levels in blood plasma and serum, and saliva of juvenile pigs in response to acute systemic inflammation. The objectives were to: (1) validate an analytical method for quantifying cytokines in serum; (2) assess the reliability of serum compared to plasma for cytokine quantification; and (3) explore the potential of saliva as a non-invasive alternative for cytokine measurement. Changes in 13 cytokines (IFN-γ, TNF-α, IL-1α, IL-1β, IL-1ra, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-18 and GM-CSF) were analyzed in serum and saliva samples collected over a 72 h period following lipopolysaccharide (LPS) infusion to induce an acute inflammatory response in 10 juvenile pigs (~28 kg BW). EDTA plasma was collected over the same time period, and a subset of four cytokines (IL-1β, IL-6, IL-10 and IFN-γ) was analyzed to assess correlations with serum concentrations. A strong positive correlation was observed between serum and EDTA plasma levels of IL-1β, IL-6, IL-10 and IFN-γ (r = 0.91-1.00,
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Registered trials
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