Evidence map›Paper›PMID 41600696›Full record

ArticleVeterinary sciences2026

Identification and Characterization of Canine Parvoviruses and Emergence of Canine Bocavirus and Bufavirus from Diarrheic Dogs in Sichuan Province, China.

Siyu Liu, Xiaoqi Li, Yuxin Zhou, Shuangshuang Song, Yuyan Huang, Mengjie Che, Xin Lei, Iram Laghari, Mingyue Wu, Ruilin Han and 5 more

Abstract read
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In one paragraph

Article in Veterinary sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Siyu LiuKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Xiaoqi LiKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Yuxin ZhouKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Shuangshuang SongKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Yuyan HuangKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Mengjie CheKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Xin LeiKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Iram LaghariKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Mingyue WuKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Ruilin HanKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Haifeng LiuKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-7495-9332
Ziyao ZhouKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Guangneng PengKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-9898-5754
Kun ZhangKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Zhijun ZhongKey Laboratory of Animal Disease and Human Health of Sichuan, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine parvovirus (CPV) is the primary cause of viral enteritis in dogs, while canine bocavirus (CBoV) and canine bufavirus (CBuV) have emerged as significant components of the canine enteric virome. Previous studies on CPV in Sichuan had limited geographic coverage and sample size, and lacked data on CBoV and CBuV. This study used PCR to investigate the genetic diversity of CPV, CBoV and CBuV and to examine their co-infection status in diarrheic dogs across five regions of Sichuan between 2020 and 2022. The results revealed that CPV-2 was the most prevalent virus (33.3%, 48/144), while CBoV (5.56%, 8/144) and CBuV (4.17%, 6/144) were detected for the first time in Sichuan province. Genetic analysis revealed CPV-2c to be the predominant genotype (95.8% (46/48)), replacing the previously circulating strains CPV-2a and CPV-new 2a. The study also identified several typical and novel mutations in the VP2 protein in the CPV-2c strains, including Ala5Gly, Trp214Cys and Thr440Ala. Additionally, four co-infection cases (2.78%) were observed, including a triple CPV/CBoV/CBuV infection in Xichang (XC05). Phylogenetic analysis revealed genetic diversity, with CBoV strains clustering into CBoV-1 and CBoV-2 subspecies, while CBuV strains formed two distinct clusters. Our findings emphasize the need for ongoing monitoring of the dynamic epidemiological situation of CPV, CBoV and CBuV in Sichuan Province.

Indexed as

canine bocaviruscanine bufaviruscanine parvovirusphylogenetic analysisVP2

Identifiers

PMID41600696
PMCPMC12846450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.