Evidence map›Paper›PMID 41600621›Full record

ArticleToxics2026

Polybrominated Diphenyl Ether (PBDE) Serum Concentrations in Italian Women of Reproductive Age.

Annalisa Abballe, Elena De Felip, Elena Dellatte, Nicola Iacovella, Valentina Marra, Roberto Miniero, Silvia Valentini, Anna Maria Ingelido

Abstract read
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Annalisa AbballeUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-6558-8253
Elena De FelipUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.
Elena DellatteUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-1903-2948
Nicola IacovellaUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-5788-559X
Valentina MarraUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-9370-6605
Roberto MinieroUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-9041-9547
Silvia ValentiniUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-3106-8126
Anna Maria IngelidoUnit of Human Exposure to Environmental Contaminants, Department of Environment and Health, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-6664-5245

Funding

the ''Life Plus'' financial instrument (EC, DG Environment), and cofunded by the Italian National Institute of Health, and by the Ministry of the Environment, Land and Territory Project n. LIFE08 ENV/IT/000423
6 · The paper itself

Abstract

The evaluation of human exposure to environmental contaminants is a highly relevant topic for carrying out appropriate risk assessments and management. For this reason, although exposure assessment studies are continuously increasing, it is important to increase knowledge on the subject, especially when data gaps exist. Polybrominated diphenyl ethers (PBDEs) are a class of substances for which the available data in the literature are not abundant compared to other more studied contaminants. In particular, the data available for the Italian population are even more limited. This study aimed to characterize the exposure of women of reproductive age to PBDEs in different Italian regions. We focused on the study on women of reproductive age because they are a sensitive category, and, furthermore, the exposure of mothers allows us to estimate that of newborns. Study results showed that the most abundant congeners in terms of relative concentration were BDE-153 > BDE-47 > BDE-100 > BDE-99, with median estimates, respectively, of 0.670, 0.245, 0.110, and 0.100 ng/g lipid in serum samples. Overall, the average exposure of the study population to the selected flame retardants appears to be relatively low compared to other industrialized countries. The observed levels could be related to the decline of PBDE concentrations in Europe due to a ban in the European Union on most PBDE commercial technical mixtures from 2001 onwards.

Indexed as

human exposureItalyPBDEswomen of reproductive age

Identifiers

PMID41600621
PMCPMC12846057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.