ArticleToxics2026
Micronuclei and Nuclear Abnormalities in Oral Mucosa as Indicators of Genotoxicity in Healthcare Professionals.
Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
Abstract
The buccal micronucleus cytome assay (BMCyt) is a validated, non-invasive biomonitoring method used to detect early genotoxic and cytotoxic changes linked to environmental and occupational exposures. Healthcare workers, especially nurses and dentists, are routinely exposed to genotoxic agents such as anesthetic gases, cytotoxic drugs, ionizing radiation, and heavy metals. This study compared seven cytological biomarkers in exfoliated buccal cells from female nurses, dentists, and teachers to assess multivariate cytogenetic differences and potential occupational influences. Samples were collected from 32 nurses, 41 dentists, and 47 teachers, and 3000 cells per participant were evaluated for micronuclei (MN) and six additional nuclear abnormalities. Group differences were examined using MANOVA and permutation MANOVA, followed by pairwise tests, and visualized with Principal Component Analysis (PCA). Significant multivariate differences were found between nurses and both dentists and teachers (
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