Evidence map›Paper›PMID 41600411›Full record

ReviewSensors (Basel, Switzerland)2026

Nanobiosensors: A Potential Tool to Decipher the Nexus Between SARS-CoV-2 Infection and Gut Dysbiosis.

Atul Kumar Tiwari, Munesh Kumar Gupta, Siddhartha Kumar Mishra, Ramovatar Meena, Fernando Patolsky, Roger J Narayan

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Atul Kumar TiwariDepartment of Chemistry, Indian Institute of Technology (BHU), Varanasi 221005, India.ORCID 0000-0003-3188-3566
Munesh Kumar GuptaDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.ORCID 0000-0002-2107-1727
Siddhartha Kumar MishraDepartment of Biochemistry, University of Lucknow, Lucknow 226007, India.ORCID 0000-0003-1627-1377
Ramovatar MeenaSchool of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110067, India.ORCID 0000-0002-3703-3274
Fernando PatolskySchool of Chemistry, Tel Aviv University, P.O. Box 39040, Tel Aviv 6997801, Israel.ORCID 0000-0002-1382-5357
Roger J NarayanJoint Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC 27695, USA.ORCID 0000-0002-4876-9869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of SARS-CoV-2 posed a great global threat and emphasized the urgent need for diagnostic tools that are rapid, reliable, sensitive and capable of real-time monitoring of SARS-CoV-2 infections. Recent investigations have identified a potential connection between SARS-CoV-2 infection and gut dysbiosis, highlighting the sophisticated interplay between the virus and the host microbiome. This review article discusses the eminence of nanobiosensors, as state-of-the-art tools, to investigate and clarify the connection between SARS-CoV-2 pathogenesis and gut microbiome imbalance. Nanobiosensors are uniquely advantageous owing to their sensitivity, selectivity, specificity, and reliable monitoring capabilities, making them well-suited for identifying both viral particles and microbial markers in biological samples. We explored a range of nanobiosensor platforms and their potential use for concurrently monitoring the gut dysbiosis induced by different pathological conditions. Additionally, we explore how advanced sensing technologies can shed light on the mechanisms driving virus-induced dysbiosis, and the implications for disease progression and patient outcomes. The integration of nanobiosensors with microfluidic devices and artificial intelligence algorithms has also been explored, highlighting the potential of developing point-of-care diagnostic tools that provide comprehensive insights into both viral infection and gut health. Utilizing nanotechnology, scientists and healthcare professionals may gain a more profound insight into the complex interaction dynamics between SARS-CoV-2 infection and the gut microenvironment. This could pave the way for enhanced diagnostic and prognostic approaches, treatment courses, and patient care for COVID-19.

Indexed as

Biosensing TechniquesCOVID-19DysbiosisGastrointestinal MicrobiomeNanotechnologyHumansPandemicsSARS-CoV-2dysbiosisgut microbiomenanobiosensorsnanotechnologySARS-CoV-2

Identifiers

PMID41600411
PMCPMC12845917

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.