ArticleSensors (Basel, Switzerland)2026
Bioinformatics-Inspired IMU Stride Sequence Modeling for Fatigue Detection Using Spectral-Entropy Features and Hybrid AI in Performance Sports.
Article in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Wearable inertial measurement units (IMUs) provide an accessible means of monitoring fatigue-related changes in running biomechanics, yet most existing methods rely on limited feature sets, lack personalization, or fail to generalize across individuals. This study introduces a bioinformatics-inspired stride sequence modeling framework that integrates spectral-entropy features, sample entropy, frequency-domain descriptors, and mixed-effects statistical modeling to detect fatigue using a single lumbar-mounted IMU. Nineteen recreational runners completed non-fatigued and fatigued 400 m runs, from which we extracted stride-level features and evaluated (1) population-level fatigue classification via global leave-one-participant-out (LOPO) models and (2) individualized fatigue detection through supervised participant-specific models and non-fatigued-only anomaly detection. Mixed-effects models revealed robust and multidimensional fatigue effects across key biomechanical features, with large standardized effect sizes (Cohen's d up to 1.35) and substantial variance uniquely explained by fatigue (partial R
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