ArticlePlants (Basel, Switzerland)2026
Uncovering the Genetic Basis of Grain Protein Content and Wet Gluten Content in Common Wheat (
Article in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Improving wheat processing quality is a crucial objective in modern wheat breeding. Among various quality parameters, grain protein content (GPC) and wet gluten content (WGC) significantly influence the end-use quality of flour. These traits are controlled by multiple minor effect genes and highly influenced by environmental factors. Identifying stable and major-effect genetic loci and developing breeder-friendly molecular markers are of great significance for breeding high-quality wheat varieties. In this study, we evaluated the GPC and WGC of 310 diverse wheat varieties, mainly from China and Europe, across four environments. Genotyping was performed using the wheat 100K SNP chip, and genome-wide association analysis (GWAS) was employed to identify stable loci with substantial effects. In total, four loci for GPC were identified on chromosomes 1A, 3A, 3B, and 4B, with explained phenotypic variation (PVE) ranging from 6.0 to 8.4%. In addition, three loci for WGC were identified on chromosomes 4B, 5A, and 5D, which explained 7.0-10.0% of the PVE. Among these, three loci coincided with known genes or quantitative trait loci (QTL), whereas
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