ArticlePharmaceuticals (Basel, Switzerland)2025
Development of Novel Proline- and Pipecolic Acid-Based Allosteric Inhibitors of Dengue and Zika Virus NS2B/NS3 Protease.
Josè Starvaggi, Carla Di Chio, Johannes Lang, Valentina Belgiovine, Daniela Trisciuzzi, Santo Previti, Christian Klein, Orazio Nicolotti, Salvatore Di Maro, Maria Zappalà and 1 more
Abstract read
In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Josè StarvaggiDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0009-0000-9875-7383 Carla Di ChioDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-3191-3932 Johannes LangInstitute of Pharmacy and Molecular Biotecnology, University of Heidelberg, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.
Valentina BelgiovineDepartment of Pharmacy-Drug Science, University of Bari, Via Amendola 173, 70126 Bary, Italy.
Daniela TrisciuzziDepartment of Pharmacy-Drug Science, University of Bari, Via Amendola 173, 70126 Bary, Italy.ORCID 0000-0002-8799-6562 Santo PrevitiDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0001-8473-3321 Christian KleinInstitute of Pharmacy and Molecular Biotecnology, University of Heidelberg, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany.
Orazio NicolottiDepartment of Pharmacy-Drug Science, University of Bari, Via Amendola 173, 70126 Bary, Italy.ORCID 0000-0001-6533-5539 Salvatore Di MaroDepartment of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania "Luigi Vanvitelli", Via A. Vivaldi, 43, 81100 Caserta, Italy.ORCID 0000-0002-9286-4433 Maria ZappalàDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-8942-797X Roberta EttariDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0001-9020-2068 Funding
PRIN_2022PNRR P2022KCW3LP2022KCW3L_001 and P2022KCW3LP2022KCW3L_002
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
allosteric inhibitorsdengue virusNS2B/NS3 serine proteaseZika virus
Identifiers
PMID41599626
PMCPMC12845239
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390