BAM 15 Exerts Molluscicidal Effects on

Liping Wang, Haonan Yu, Guoli Qu, Jiankun Jin, Jie Wang, Yuntian Xing

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liping WangWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.ORCID 0009-0003-9741-7610

Haonan YuNational Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.ORCID 0009-0008-6214-7848

Guoli QuNational Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.

Jiankun JinNational Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.ORCID 0009-0002-8424-4741

Jie WangNational Health Commission Key Laboratory of Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi 214064, China.

Yuntian XingWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.ORCID 0000-0002-3796-1396

Funding

The Jiangsu Province Capability Improvement Project through Science, Technology and Education No. ZDXYS202207The Open Project of National Health Commission Key Laboratory of Parasitic Disease Control and Prevention No. wk023-009

6 · The paper itself

Abstract

backgroundThe golden apple snail (

resultsBAM 15 possesses strong molluscicidal activity against

conclusionsOur findings reveal that BAM 15 operates via a three-stage mechanism: (1) it disrupts membrane potential (ΔΨm) and impairs ATP production, severely disturbing energy metabolism; (2) energy deficits stimulate excessive electron transport chain activity, generating reactive oxygen species (ROS) and initiating oxidative stress; (3) persistent metabolic imbalance and oxidative damage culminate in extensive tissue injury. These results identify BAM 15 as a promising candidate for molluscicide development.

Indexed as

Energy MetabolismMolluscacidesNiclosamideOxidative StressSnailsAnimalsMembrane Potential, MitochondrialMetabolomicsProteomicsReactive Oxygen SpeciesMolluscacidesNiclosamideReactive Oxygen SpeciesBAM 15metabolomicsmolluscicidal mechanismmolluscicidePomacea canaliculataproteomics

Identifiers

PMID41599409

DOI10.3390/molecules31020361

PMCPMC12843921

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.