Evidence map›Paper›PMID 41599314›Full record

ArticleMolecules (Basel, Switzerland)2026

Design, Synthesis, and Anti-Hepatic Fibrosis Evaluation of Cordycepin Derivatives.

Wenfang Pan, Siqi Liu, Yuanchen Zhong, Bixi Tang, Yi Zang, Yuanchao Xie

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenfang PanLingang Laboratory, Shanghai 200031, China.
Siqi LiuLingang Laboratory, Shanghai 200031, China.
Yuanchen ZhongLingang Laboratory, Shanghai 200031, China.
Bixi TangLingang Laboratory, Shanghai 200031, China.
Yi ZangLingang Laboratory, Shanghai 200031, China.
Yuanchao XieLingang Laboratory, Shanghai 200031, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of hepatic stellate cells (HSCs) featuring upregulated expression of α-smooth muscle actin (α-SMA) is recognized as a key driver for hepatic fibrosis, which provides a promising strategy for seeking anti-liver fibrogenic agents via suppressing the activation event. In this study, we designed and synthesized twenty-eight cordycepin derivatives through structural modifications at the C2 position and the C6-NH

Indexed as

DeoxyadenosinesDrug DesignLiver CirrhosisActinsAMP-Activated Protein KinasesCell LineCell MovementHepatic Stellate CellsHumansSignal TransductionActinsAMP-Activated Protein KinasescordycepinDeoxyadenosinesAMPKcordycepinhepatic fibrosisHSCs activationα-SMA

Identifiers

PMID41599314
PMCPMC12844307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.