Evidence map›Paper›PMID 41599237›Full record

ReviewPharmaceutics2026

Albumin Nanoparticles as Multifunctional Carriers for Advanced Therapeutics.

Bogusława Konopska, Janusz Sokołowski, Anna Woźniak, Mikołaj Kondracki, Jakub Federowicz, Wojciech Grodzki, Agnieszka Bronowicka-Szydełko, Katarzyna Madziarska

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bogusława KonopskaDepartment of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-1388-1989
Janusz SokołowskiDepartment of Emergency Medicine, Faculty of Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-2992-5499
Anna WoźniakClinical Department of Diabetology, Hypertension and Internal Diseases, Faculty of Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0001-9728-2603
Mikołaj KondrackiFaculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Jakub FederowiczFaculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Wojciech GrodzkiFaculty of Medicine, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Agnieszka Bronowicka-SzydełkoDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-369 Wroclaw, Poland.ORCID 0000-0001-9967-036X
Katarzyna MadziarskaClinical Department of Diabetology, Hypertension and Internal Diseases, Faculty of Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-3624-3691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern medicine requires effective, continuous, and safe therapies, which largely depend on the targeted delivery and activity of the drug. This goal can be achieved by designing drug delivery systems with improved pharmacokinetic properties and enhanced drug transport to the affected tissue. Human serum albumin (HSA) is an attractive carrier for the synthesis of therapeutic nanoparticles, several of which have already been approved by the United States Food and Drug Administration (FDA). The success of Abraxane as an effective treatment for metastatic breast cancer and non-small cell lung carcinoma, the application of Optison in ultrasound imaging, and the use of Nanocoll as an agent for SPECT diagnostics in sentinel node localisation confirm the strong potential of albumin-based systems. Further benefits are expected in patients with soft tissue cancers, as LadRx is seeking FDA marketing approval for Aldoxorubicin. The future of oncology lies in theranostics, which combines a tumour-localising factor on one platform with a drug targeting cancer cells and a factor that activates the cytotoxicity of the drug after it reaches the target tissue. This article presents recent advancements in albumin-based nanoparticles for drug delivery, targeting, and imaging. It also briefly discusses methods of synthesis and surface modification of albumin nanocarriers to enable targeted delivery to pathological sites. Finally, it outlines the latest approaches in multimodal theranostic platforms, highlighting albumin's potential to improve cancer therapy.

Indexed as

albumindrug delivery systemsnanoparticlestheranostics

Identifiers

PMID41599237
PMCPMC12845301

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.