Evidence map›Paper›PMID 41599190›Full record

ArticlePharmaceutics2026

Novel Repurposing of Empagliflozin-Loaded Buccal Composite (Chitosan/Silk Fibroin/Poly(lactic acid)) Nanofibers for Alzheimer's Disease Management via Modulation of Aβ-AGER-p-tau Pathway.

Walaa A El-Dakroury, Samar A Salim, Abdelrahman R Said, Gihan F Asaad, Mohamed F Abdelhameed, Marwa E Shabana, Mohamed M Ibrahim, Sara G Abualmajd, Haidy H Mosaad, Aliaa A Salama and 4 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Walaa A El-DakrouryDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.ORCID 0000-0002-8162-8515
Samar A SalimNanotechnology Research Center (NTRC), The British University in Egypt (BUE), El-Sherouk City 11837, Cairo, Egypt.ORCID 0000-0002-0980-6006
Abdelrahman R SaidDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.ORCID 0009-0000-6260-6209
Gihan F AsaadDepartment of Pharmacology, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Giza 12622, Cairo, Egypt.ORCID 0000-0002-7679-5968
Mohamed F AbdelhameedDepartment of Pharmacology, Medical Research and Clinical Studies Institute, National Research Centre, Dokki, Giza 12622, Cairo, Egypt.ORCID 0000-0001-6100-6498
Marwa E ShabanaPathology Department, National Research Centre, Dokki, Giza 12622, Cairo, Egypt.
Mohamed M IbrahimFaculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.
Sara G AbualmajdFaculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.
Haidy H MosaadFaculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.
Aliaa A SalamaFaculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.
Shrouk E AsranFaculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.
Mayar L AmerFaculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.
Ahmed S DoghishBiochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City 11231, Cairo, Egypt.ORCID 0000-0002-0136-7096
Fatma Sa'eed El-TokhyDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseasechitosanempagliflozinfibroinnanofiberspolylactic acid

Identifiers

PMID41599190
PMCPMC12844634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.