Evidence map›Paper›PMID 41599167›Full record

ReviewPharmaceutics2026

Quality by Design for the Nanoformulation of Cosmeceuticals.

Gerardo Leyva-Gómez, Elizabeth Piñón-Segundo, Zaida Urban-Morlan, Nancy E Magaña-Vergara, David Quintanar-Guerrero, Betzabeth Jaime-Escalante, Néstor Mendoza-Muñoz

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gerardo Leyva-GómezDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0002-7940-1100
Elizabeth Piñón-SegundoLaboratorio de Sistemas Farmacéuticos de Liberación Modificada, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54714, Mexico.
Zaida Urban-MorlanCentro de Información de Medicamentos y Farmacia Clínica, Facultad de Química, Universidad Autónoma de Yucatán, Mérida 97069, Mexico.ORCID 0000-0001-6796-5147
Nancy E Magaña-VergaraSECIHTI Investigadores e Investigadoras por México, Facultad de Ciencias Químicas, Universidad de Colima, Colima 28400, Mexico.ORCID 0000-0002-7079-0752
David Quintanar-GuerreroLaboratorio de Investigación y Posgrado en Tecnología Farmacéutica, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli 54740, Mexico.ORCID 0000-0002-0881-0943
Betzabeth Jaime-EscalanteDepartamento de Sistemas Biológicos, Universidad Autónoma Metropolitana, Ciudad de México 04960, Mexico.
Néstor Mendoza-MuñozLaboratorio de Farmacia, Facultad de Ciencias Químicas, Universidad de Colima, Colima 28400, Mexico.ORCID 0000-0003-2252-6997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cosmeceuticals are cosmetic formulations that are intended to alleviate skin conditions that affect its appearance and functionality. They are not considered medications but contain molecules that exert biological action on the skin beyond traditional cosmetic actions. Sometimes, the bioactives used have limitations for transdermal passage, and it has been suggested that the use of nanocarriers can increase the effectiveness of cosmeceutical products. The degree of sophistication of nanocosmeceuticals requires that safety and efficacy aspects be verified before going on the market. In this regard, the application of the Quality by Design (QbD) approach during product development ensures that products meet the consumer needs in full. This review analyzes the implementation of QbD in the development of nanocosmeceuticals, considering the main characteristics of the most used bioactive groups and nanocarriers that have proven to be ideal vehicles for topical and transdermal applications.

Indexed as

bioactivescosmeceuticalsnanocarriersnanotechnologyQuality by Design

Identifiers

PMID41599167
PMCPMC12845242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.