About Zika Virus (ZIKV). Reply to Weidmann et al. Zika Virus Pathogenicity Versus Transmissibility. Comment on "Roozitalab et al. Distinct Virologic Properties of African and Epidemic Zika Virus Strains: The Role of the Envelope Protein in Viral Entry, Immune Activation, and Neuropathogenesis.

Ashkan Roozitalab, Chenyu Zhang, Jiantao Zhang, Ge Li, Chengyu Yang, Wangheng Hou, Qiyi Tang, Richard Y Zhao

Abstract readCommentLetter

In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ashkan RoozitalabDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-2686-5171

Chenyu ZhangDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Jiantao ZhangDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Ge LiDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

Chengyu YangState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen 361102, China.

Wangheng HouState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University, Xiamen 361102, China.

Qiyi TangDepartment of Microbiology, Howard University College of Medicine, Washington, DC 20059, USA.ORCID 0000-0002-6487-2356

Richard Y ZhaoDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0003-3424-2852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors emphasize on the long-standing codon adaptation of African ZIKV lineages to primate hosts, as this evolutionary framework helps explain several characteristics of African strains [...].

Indexed as

Viral Envelope ProteinsZika VirusZika Virus InfectionAfricaAnimalsHumansVirus InternalizationViral Envelope Proteins

Identifiers

PMID41599052

DOI10.3390/pathogens15010068

PMCPMC12845413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.