Evidence map›Paper›PMID 41599041›Full record

ReviewPathogens (Basel, Switzerland)2026

Iron Regulatory Mechanism IRE/IRP-like in Two Protozoa of Importance to Human Health,

Jesús Gabriel León-Beltrán, Sarita Montaño, Rossana Arroyo, Daniela Estrada-Ramírez, Nidia León-Sicairos, Adrián Canizalez-Román, María Angélica Sánchez-González, José Antonio Garzón-Tiznado, Claudia León-Sicairos

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trichomonas vaginalis cathepsin D-like aspartic proteinase (Tv-CatD) is regulated by iron at different levels.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jesús Gabriel León-BeltránPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0009-0001-6747-9410
Sarita MontañoPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0000-0002-0420-4268
Rossana ArroyoDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav), Av. IPN No. 2508, Colonia San Pedro Zacatenco, Mexico City 07360, Mexico.ORCID 0000-0002-8193-9700
Daniela Estrada-RamírezPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.
Nidia León-SicairosPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0000-0003-1470-3383
Adrián Canizalez-RománPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0000-0001-8605-0639
María Angélica Sánchez-GonzálezPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0009-0009-7176-3244
José Antonio Garzón-TiznadoPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0000-0003-0423-3349
Claudia León-SicairosPrograma Regional del Noroeste para el Posgrado en Biotecnología de la Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Sinaloa, Av. de las Américas y Josefa Ortíz (Cd. Universitaria), Culiacán 80030, Mexico.ORCID 0000-0002-4175-5763

Funding

SECIHTI 51241UAS PROFAPI
6 · The paper itself

Abstract

Protozoa use iron to grow, feed, and cause harm through elaborate mechanisms to obtain it from the host. In addition, expression of virulence genes is affected by iron. In

Indexed as

Entamoeba histolyticaGiardia lambliaIronIron-Regulatory ProteinsAnimalsGene Expression RegulationHumansProtozoan ProteinsIronIron-Regulatory ProteinsProtozoan ProteinsEntamoeba histolyticaGiardia duodenalisIREsironregulation

Identifiers

PMID41599041
PMCPMC12845348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.