Evidence map›Paper›PMID 41598996›Full record

ArticlePathogens (Basel, Switzerland)2025

Development of Approaches for Transgene Expression in the Pathogenic Free-Living Amoeba

Caroline M Palmentiero, Jillian E M McKeon, Colm P Roster, James C Morris

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Caroline M PalmentieroEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson University, Clemson, SC 29634, USA.ORCID 0009-0006-6843-937X
Jillian E M McKeonEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0002-4872-082X
Colm P RosterEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson University, Clemson, SC 29634, USA.ORCID 0009-0007-3204-6766
James C MorrisEukaryotic Pathogens Innovation Center, Department of Genetics and Biochemistry, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0003-2515-5714

Funding

Regulation of Cryptosporidium DevelopmentP20GM146584 · NIGMS · CLEMSON UNIVERSITY · PI KERRY Scot SMITH · 2022 to 2026
$13.5M
Approaches for genetic manipulation of Naegleria fowleriR21AI175463 · NIAID · CLEMSON UNIVERSITY · PI MORRIS, JAMES CULVIN · 2023 to 2024
$419k
NIAID NIH HHS R21 AI175463NIGMS NIH HHS P20 GM146584NIH HHS 1P20GM146584-27NIH HHS 1R21AI171217-26NIH HHS 1R21AI175463-24
6 · The paper itself

Abstract

The absence of molecular tools for manipulation of gene expression in the pathogenic free-living amoeba

Indexed as

Gene ExpressionNaegleria fowleriTransgenesAcetyltransferasesLuminescent ProteinsPlasmidsRed Fluorescent ProteinTransfectionAcetyltransferasesLuminescent Proteinspuromycin N-acetyltransferaseRed Fluorescent Proteinfluorescent proteinsNaegleria fowleriselectable markerstransgenetransgenic

Identifiers

PMID41598996
PMCPMC12845041

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.