Evidence map›Paper›PMID 41598221›Full record

ArticleLife (Basel, Switzerland)2026

Visual Large Language Models in Radiology: A Systematic Multimodel Evaluation of Diagnostic Accuracy and Hallucinations.

Marc Sebastian von der Stück, Roman Vuskov, Simon Westfechtel, Robert Siepmann, Christiane Kuhl, Daniel Truhn, Sven Nebelung

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marc Sebastian von der StückDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0009-0004-2801-3679
Roman VuskovDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Simon WestfechtelDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-7050-9924
Robert SiepmannDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Daniel TruhnDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.

Funding

and the German Federal Ministry of Education and Research 01KD2215ADeutsche Forschungsgemeinschaft (DFG) LI 3893/6-1Deutsche Forschungsgemeinschaft (DFG) NE 2136/3-1Deutsche Forschungsgemeinschaft (DFG) TR 1700/7-1European Union's Horizon Europe programme (ODELIA) 101057091German Federal Ministry of Education and Research 031L0312A
6 · The paper itself

Abstract

Visual large language models (VLLMs) are discussed as potential tools for assisting radiologists in image interpretation, yet their clinical value remains unclear. This study provides a systematic and comprehensive comparison of general-purpose and biomedical VLLMs in radiology. We evaluated 180 representative clinical images with validated reference diagnoses (radiography, CT, MRI; 60 each) using seven VLLMs (ChatGPT-4o, Gemini 2.0, Claude Sonnet 3.7, Perplexity AI, Google Vision AI, LLaVA-1.6, LLaVA-Med-v1.5). Each model interpreted the image without and with clinical context. Mixed-effects logistic regression models assessed the influence of model, modality, and context on diagnostic performance and hallucinations (fabricated findings or misidentifications). Diagnostic accuracy varied significantly across all dimensions (

Indexed as

machine learningmagnetic resonance imagingtomography (X-ray-computed)

Identifiers

PMID41598221
PMCPMC12842777

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.