Evidence map›Paper›PMID 41598159›Full record

ArticleLife (Basel, Switzerland)2025

Combined Pharmacological and Pneumatic Displacement Therapy for Sub-Macular Haemorrhage Secondary to Age-Related Macular Degeneration: A Case Series and Review of the Literature.

Agnieszka Kudasiewicz-Kardaszewska, Małgorzata Anna Ozimek, Tomasz Urbański, Kinga Jamontt, Aleksander Tkaczenko, Karolina Bonińska, Sławomir Cisiecki

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Agnieszka Kudasiewicz-KardaszewskaOCHO Medical Group, Zagorski Eye Surgery Centre in Nowy Sącz, 33-300 Nowy Sącz, Poland.ORCID 0009-0009-8940-4362
Małgorzata Anna OzimekOCHO Medical Group, Zagorski Eye Surgery Centre in Nowy Sącz, 33-300 Nowy Sącz, Poland.
Tomasz UrbańskiOCHO Medical Group, Zagorski Eye Surgery Centre in Nowy Sącz, 33-300 Nowy Sącz, Poland.
Kinga JamonttOCHO Medical Group, Zagorski Eye Surgery Centre in Nowy Sącz, 33-300 Nowy Sącz, Poland.
Aleksander TkaczenkoOCHO Medical Group, Zagorski Eye Surgery Centre in Nowy Sącz, 33-300 Nowy Sącz, Poland.
Karolina BonińskaDepartment of Opththalmology, Miejskie Centrum Medyczne im. Karola Jonschera, 93-113 Łódź, Poland.
Sławomir CisieckiDepartment of Opththalmology, Miejskie Centrum Medyczne im. Karola Jonschera, 93-113 Łódź, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to present the clinical outcomes of a combined pharmacological and gas-assisted treatment for sub-macular haemorrhage secondary to neovascular age-related macular degeneration (nAMD).

methodsThis retrospective case series included ten eyes with sub-macular haemorrhage (SMH) treated between January 2024 and September 2025. All patients received intravitreal alteplase (100 µg) and C

resultsMean BCVA improved from 0.99 ± 0.21 logMAR at baseline to 0.89 ± 0.20 at 7-14 days, 0.80 ± 0.20 at 1 month, 0.60 ± 0.18 at 3 months, and 0.53 ± 0.20 at 6 months (

conclusionCombined intravitreal alteplase and C

Indexed as

afliberceptalteplase)anti-VEGFexpansile gasneovascular age-related macular degeneration (nAMD)sub-macular haemorrhagetissue plasminogen activator (tPA

Identifiers

PMID41598159
PMCPMC12842607

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.