Evidence map›Paper›PMID 41598123›Full record

ArticleMaterials (Basel, Switzerland)2026

Electrospun PVA/CS/HA/BA Nanofiber Scaffolds with Enhanced Mechanical Stability and Antifungal Activity for Bone Tissue Engineering.

Yagizer Yavuz, Ilyas Kartal, Sumeyye Cesur, Zehra Kanli, Elif Kaya, Gulgun Tinaz, Oguzhan Gunduz

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yagizer YavuzDepartment of Metallurgical and Materials Engineering, Institute of Pure and Applied Sciences, Marmara University, Istanbul 34722, Turkey.ORCID 0000-0001-8214-4005
Ilyas KartalDepartment of Metallurgical and Materials Engineering, Faculty of Technology, Marmara University, Istanbul 34854, Turkey.ORCID 0000-0001-9677-477X
Sumeyye CesurCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34854, Turkey.
Zehra KanliCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34854, Turkey.ORCID 0000-0001-5169-9999
Elif KayaDepartment of Biochemistry, Faculty of Pharmacy, Health Sciences Institute, Marmara University, Istanbul 34854, Turkey.
Gulgun TinazDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Marmara University, Istanbul 34854, Turkey.ORCID 0000-0003-1080-4419
Oguzhan GunduzCenter for Nanotechnology & Biomaterials Application and Research (NBUAM), Marmara University, Istanbul 34854, Turkey.ORCID 0000-0002-4926-6489

Funding

Marmara University Scientific Research Project Commission FDK-2024-11223
6 · The paper itself

Abstract

In this study, we created multifunctional bone tissue engineering scaffolds that combine prophylactic antifungal action with structural support. We produced PVA/CS/HA/BA nanofiber matrices via a specifically designed electrospinning technique to stop early cross-linking. Through SEM, our examination of fiber shape revealed diameters ranging from 178 ± 53 nm to 330 ± 69 nm. We discovered that this variation was closely correlated with the Boric Acid (BA) level. Our EDS and FTIR studies further showed that HA and BA were effectively mixed, with a specific focus on the production of borate-ester linkages inside the network. Mechanical examination revealed that 0.25 wt.% BA maximizes the tensile strength at 9.15 MPa, thereby closely matching HA-reinforced standards, while HA incorporation improved thermal stability. Moreover, in vitro hFOB experiments showed sustained cytocompatibility at 0.25 wt.% BA. While 0.5 wt.% BA showed strong antifungal action against

Indexed as

antifungal scaffoldsCandida albicanscross-linking behaviorscaffold

Identifiers

PMID41598123
PMCPMC12843223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.