Evidence map›Paper›PMID 41597690›Full record

ArticleMicroorganisms2026

Epidemiology of Rotavirus and Its Association with Other Etiological Agents of Enteric Infections in the Mexican Child Population (0-5 Years).

Larissa Fernandes-Matano, Luis Antonio Uribe-Noguez, Julio Elias Alvarado-Yaah, Angel Gustavo Salas-Lais, Clara Esperanza Santacruz-Tinoco, José Esteban Muñoz-Medina, Andrea Santos Coy-Arechavaleta

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Larissa Fernandes-MatanoDivisión de Laboratorios Especializados, Instituto Mexicano del Seguro Social, Mexico City 07760, Mexico.ORCID 0000-0001-7599-1046
Luis Antonio Uribe-NoguezLaboratorio Central de Epidemiología, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.ORCID 0000-0003-2452-782X
Julio Elias Alvarado-YaahLaboratorio Central de Epidemiología, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.ORCID 0000-0002-7230-9045
Angel Gustavo Salas-LaisDivisión de Laboratorios Especializados, Instituto Mexicano del Seguro Social, Mexico City 07760, Mexico.ORCID 0000-0003-3757-6209
Clara Esperanza Santacruz-TinocoDivisión de Laboratorios Especializados, Instituto Mexicano del Seguro Social, Mexico City 07760, Mexico.ORCID 0000-0003-0039-986X
José Esteban Muñoz-MedinaDivisión de Laboratorios Especializados, Instituto Mexicano del Seguro Social, Mexico City 07760, Mexico.ORCID 0000-0002-1289-4457
Andrea Santos Coy-ArechavaletaLaboratorio Central de Epidemiología, Instituto Mexicano del Seguro Social, Mexico City 02990, Mexico.ORCID 0000-0001-7096-2545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrointestinal infections are a major cause of morbidity worldwide. Rotavirus (RVA) is the most frequent cause of severe diarrheal disease in children and is associated with high direct and indirect costs. Symptoms of RVA infection are nonspecific, so diagnostic confirmation requires laboratory testing, which is not routinely performed due to its high cost. For this reason, only a small proportion of hospitalizations are correctly classified. In this context, this study was conducted to determine the prevalence of RVA and 19 other potential etiological agents in 642 samples from pediatric patients with gastrointestinal symptoms at the Social Security Mexican Institute (IMSS). The findings revealed a prevalence of RVA of 26.8%. When analyzing the 321 samples that were processed for the full panel, the positivity rate was 94.4% (for any of the etiological agents tested) and a high percentage of coinfections were detected (69.8%), including up to seven different etiological agents in the same child. The RVA was more frequent in children under 1 year of age, with higher circulation in winter and spring, while bacterial infections showed a seasonal trend in summer. The proportion of hospitalizations was higher in coinfections than in monoinfections, and RVA was the pathogen with the highest percentage of hospitalizations. The results emphasize the etiological complexity of gastrointestinal infections in the pediatric population, highlighting the importance of using multiplex diagnostic tests for appropriate clinical care and effective epidemiological control strategies.

Indexed as

coinfectionsdehydrationgastrointestinal infectionrotaviruswatery diarrhea

Identifiers

PMID41597690
PMCPMC12844301

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.