Evidence map›Paper›PMID 41597630›Full record

ArticleMicroorganisms2026

Clinical Severity and Surgical Burden in Drug Use-Associated Infective Endocarditis: A Six-Year Cohort Study.

Corina-Ioana Anton, Bogdan Mircea Petrescu, Cosmin Alexandru Buzilă, Ion Ștefan, Cristian Sorin Sima, Adrian Streinu-Cercel

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Corina-Ioana AntonDepartment of Infectious Diseases, "Dr. Carol Davila" Central Military Emergency University Hospital, 134 Calea Plevnei, 010242 Bucharest, Romania.ORCID 0009-0007-8818-9539
Bogdan Mircea PetrescuDepartment of Clinical Psychiatry, "Dr. Carol Davila" Central Military Emergency University Hospital, 134 Calea Plevnei, 010242 Bucharest, Romania.
Cosmin Alexandru BuzilăCardiovascular Surgery Department, "Dr. Carol Davila" Central Military Emergency University Hospital, 134 Calea Plevnei, 010242 Bucharest, Romania.ORCID 0009-0006-4289-178X
Ion ȘtefanDepartment of Infectious Diseases, "Dr. Carol Davila" Central Military Emergency University Hospital, 134 Calea Plevnei, 010242 Bucharest, Romania.ORCID 0000-0003-0974-2476
Cristian Sorin SimaFaculty of General Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Bvd., 050474 Bucharest, Romania.ORCID 0000-0003-2508-2551
Adrian Streinu-CercelFaculty of General Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Bvd., 050474 Bucharest, Romania.

Funding

University of Medicine and Pharmacy Carol Davila Institutional program Publish not Perish
6 · The paper itself

Abstract

Drug use-associated infective endocarditis (DUA-IE) is an increasingly important clinical problem that affects younger patients and poses substantial diagnostic, therapeutic, and surgical challenges. We conducted a retrospective cohort study of adults with definite infective endocarditis treated at a tertiary referral center between 2017 and 2022, comparing patients with DUA-IE to those with non-drug use-associated infective endocarditis. Of the 189 patients, 43 (22.8%) had DUA-IE. These patients were significantly younger and had higher rates of HIV and hepatitis C coinfections.

Indexed as

infective endocarditisinjection drug useopioid use disorderStaphylococcus aureusvalve surgery

Identifiers

PMID41597630
PMCPMC12844518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.