Evidence map›Paper›PMID 41597551›Full record

ArticleMicroorganisms2025

Comparison of Commercial Lateral Flow Immunochromatography with Phenotypic and Genotypic Assays for the Detection of Carbapenemase-Producing Gram-Negative Bacteria at Tanta University Hospitals.

Marwa S Taha, Basant Mostafa Gabr, Wafaa Abd Elaziz, Ahmed Mostafa Elgohary, Bsant S Kasem, Reham M Elkolaly, Hytham I S Elatrozy, Marwa N Emam, Asmaa S Essawy, Heba E M Sharaf Eldin and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marwa S TahaDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Tanta University, El-Geish St., Medical Campus, Tanta 31527, Egypt.ORCID 0000-0003-0298-1773
Basant Mostafa GabrDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Tanta University, El-Geish St., Medical Campus, Tanta 31527, Egypt.ORCID 0000-0002-3509-0347
Wafaa Abd ElazizDepartment of Biochemistry, Genetic Engineering and Biotechnology Division, National Research Center, Dokki, Giza 12622, Egypt.
Ahmed Mostafa ElgoharyDepartment of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.
Bsant S KasemDepartment of Clinical Pathology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0009-0001-1064-0525
Reham M ElkolalyDepartment of Chest, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0001-6568-902X
Hytham I S ElatrozyDepartment of Neurosurgery, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0001-9064-8916
Marwa N EmamDepartment of Physiology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-5211-809X
Asmaa S EssawyDepartment of Anatomy, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-9914-3372
Heba E M Sharaf EldinDepartment of Basic Dental and Medical Sciences, Faculty of Dentistry, Mutah University, Al-Karak 61710, Jordan.
Rehab A MohamedDepartment of Family Medicine, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0001-5575-0237
Mahmoud Z ElkadeemDepartment of Tropical Medicine and Infectious Disease, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-2322-1186
Sherif AbdelbakyDepartment of Tropical Medicine and Infectious Disease, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0009-0009-9433-5998
Mona Abd El-Aziz GadallahDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Tanta University, El-Geish St., Medical Campus, Tanta 31527, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is crucial to identify Enterobacterales that produce carbapenemase to treat and manage hospital infections. The suggested techniques for their identification need a lengthy wait, technical knowledge, and training. Lateral flow immunoassays (LFIAs) provide a solution to these requirements. Thus, this study compared LFIA with phenotypic and genotypic tests for carbapenemase-producing bacteria. Fifty clinical isolates of carbapenem-resistant superbugs were examined. KPC, VIM, NDM, IMP, and OXA-48-like enzymes were evaluated and compared with phenotypic tests and LFIA. Regarding the phenotypic characteristics, the mCIM was positive in 37/50 (74%), and the eCIM was positive in 21/50 (42%). Regarding using LFIA, 41 out of the total isolates (82%) gave a positive red line with one or more of the tested genes. The most frequently detected gene was

Indexed as

blaIMPblaKPCblaNDMblaOXAblaVIMcarbapenemase genescarbapenemase-producing Enterobacterales (CRE)lateral flow immunoassays (LFIAs)

Identifiers

PMID41597551
PMCPMC12843627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.