Evidence map›Paper›PMID 41597500›Full record

ArticleMedicina (Kaunas, Lithuania)2026

The Impact of Concurrent Proton Pump Inhibitors on Nivolumab Response in Metastatic Non-Small Cell Lung Cancer: A Multicenter Real-Life Study.

Engin Hendem, Mehmet Zahid Koçak, Ayşegül Merç Çetinkaya, Gülhan Dinç, Melek Çağlayan, Muzaffer Uğraklı, Dilek Çağlayan, Murat Araz, Melek Karakurt Eryılmaz, Abdullah Sakin and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Engin HendemDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0001-6970-4733
Mehmet Zahid KoçakDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0003-3085-7964
Ayşegül Merç ÇetinkayaDepartment of Medical Oncology, School of Medicine, Akdeniz University, Antalya 07070, Turkey.ORCID 0000-0003-2727-7387
Gülhan DinçDepartment of Medical Oncology, Prof. Dr. Cemil Taşcıoğlu City Hospital, İstanbul 34384, Turkey.ORCID 0009-0007-6025-7800
Melek ÇağlayanDepartment of Medical Oncology, School of Medicine, Selcuk University, Konya 42130, Turkey.ORCID 0000-0002-6043-4703
Muzaffer UğraklıDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0003-0544-6047
Dilek ÇağlayanDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0003-4629-6815
Murat ArazDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0002-4632-9501
Melek Karakurt EryılmazDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0003-2597-5931
Abdullah SakinSchool of Medicine, Medipol University, Bahçelievler, İstanbul 34196, Turkey.ORCID 0000-0003-2538-8569
Orhan Önder ErenDepartment of Medical Oncology, School of Medicine, Selcuk University, Konya 42130, Turkey.ORCID 0000-0001-6397-8207
Ali Murat TatlıDepartment of Medical Oncology, School of Medicine, Akdeniz University, Antalya 07070, Turkey.ORCID 0000-0001-9696-1102
Çağlayan GeredeliDepartment of Medical Oncology, Prof. Dr. Cemil Taşcıoğlu City Hospital, İstanbul 34384, Turkey.ORCID 0000-0002-3982-7465
Mehmet ArtaçDepartment of Medical Oncology, School of Medicine, Necmettin Erbakan University, Konya 42080, Turkey.ORCID 0000-0003-2335-3354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsNivolumabProton Pump InhibitorsAgedAged, 80 and overAntineoplastic Agents, ImmunologicalDrug InteractionsFemaleHumansImmune Checkpoint InhibitorsKaplan-Meier EstimateMaleMiddle AgedRetrospective StudiesAntineoplastic Agents, ImmunologicalImmune Checkpoint InhibitorsNivolumabProton Pump InhibitorsCarcinomadrug interactionsmicrobiotanivolumabnon-small-cell lungoverall survivalprogression-free survivalproton pump inhibitors

Identifiers

PMID41597500
PMCPMC12843493

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.