Evidence map›Paper›PMID 41597427›Full record

ArticleMedicina (Kaunas, Lithuania)2026

Toll-like Receptor 7/8 Agonists Exert Antitumor Effect in a Mouse Melanoma Model.

Gheorghita Isvoranu, Mihaela Surcel, Ana-Maria Enciu, Adriana Narcisa Munteanu, Monica Neagu, Andrei Marian Niculae, Gabriela Chiritoiu, Cristian V A Munteanu, Marioara Chiritoiu-Butnaru

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gheorghita Isvoranu'Victor Babeș' National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-2185-019X
Mihaela Surcel'Victor Babeș' National Institute of Pathology, 050096 Bucharest, Romania.
Ana-Maria Enciu'Victor Babeș' National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-8122-1096
Adriana Narcisa Munteanu'Victor Babeș' National Institute of Pathology, 050096 Bucharest, Romania.
Monica Neagu'Victor Babeș' National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0001-9339-2805
Andrei Marian Niculae'Victor Babeș' National Institute of Pathology, 050096 Bucharest, Romania.
Gabriela ChiritoiuInstitute of Biochemistry of the Romanian Academy, 060031 Bucharest, Romania.ORCID 0000-0002-6321-6373
Cristian V A MunteanuInstitute of Biochemistry of the Romanian Academy, 060031 Bucharest, Romania.ORCID 0000-0002-2998-0458
Marioara Chiritoiu-ButnaruInstitute of Biochemistry of the Romanian Academy, 060031 Bucharest, Romania.ORCID 0000-0003-2064-2003

Funding

Romanian Ministry of Education and Research and CNCS-UEFISCDI PN 18.21.02.01, PN 23.16.02.02 and PN-IV-P2-2.1-TE-2023-1169
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsMelanomaToll-Like Receptor 7Toll-Like Receptor 8AminoquinolinesAnimalsDisease Models, AnimalImidazolesImiquimodKiller Cells, NaturalMembrane GlycoproteinsMiceMice, Inbred C57BLToll-Like Receptor AgonistsAminoquinolinesAntineoplastic AgentsgardiquimodImidazolesImiquimodMembrane GlycoproteinsTlr7 protein, mouseToll-Like Receptor 7Toll-Like Receptor 8Toll-Like Receptor AgonistsgardiquimodimiquimodmelanomaNK cellssubcutaneous melanoma mouse modelToll-like receptors

Identifiers

PMID41597427
PMCPMC12843957

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.