Evidence map›Paper›PMID 41597396›Full record

ReviewMedicina (Kaunas, Lithuania)2026

Intracavernous Injection Therapy as Second-Line Treatment for ED After Radical Prostatectomy: A Literature Review.

Adrian George Vlaicu, Cristian Mirvald, Salam Najjar, Radion Garaz, Igor Tsaur, Ioanel Sinescu, Cristian Surcel

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adrian George VlaicuDepartment of Urology, "C.F.2" Hospital, 011464 Bucharest, Romania.ORCID 0009-0002-3461-9170
Cristian MirvaldFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-7278-5551
Salam NajjarNord Hospital, 010948 Bucharest, Romania.
Radion GarazDepartment of Urology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-3473-4446
Igor TsaurDepartment of Urology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-5107-3523
Ioanel SinescuFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Cristian SurcelFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erectile dysfunction (ED) is a frequent and significant complication of radical prostatectomy that impacts patients' quality of life. Intracavernous injection treatment has become an important approach to post-prostatectomy ED, providing an immediate and proven means of regaining erectile function in men who are unresponsive to oral phosphodiesterase type 5 inhibitors. The scope of this article is to discuss the mechanisms, efficacy, and safety of ICI treatments using vasoactive compounds as a second-line treatment for ED after radical prostatectomy. We consider clinical results, satisfaction, and compliance, as well as predictors of success, like nerve-sparing procedures. Through our interpretation of evidence and clinical experience, ICI therapy is a cornerstone of penile rehabilitation and ED management following radical prostatectomy. Also, the prospects for further treatment optimization and patient outcomes are discussed.

Indexed as

Erectile DysfunctionProstatectomyVasodilator AgentsHumansInjectionsMalePapaverinePhosphodiesterase 5 InhibitorsTreatment OutcomePapaverinePhosphodiesterase 5 InhibitorsVasodilator Agentserectile dysfunctionintracavernous injectionsradical prostatectomy

Identifiers

PMID41597396
PMCPMC12843799

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.