Evidence map›Paper›PMID 41597204›Full record

ArticleCells2026

Pancreatic Cancer Stem Cells Co-Expressing SOX2, OCT4, and TERT

Erika Curiel-Gomez, Damaris P Romero-Rodriguez, Mauricio Rodriguez-Dorantes, Vilma Maldonado, Jorge Melendez-Zajgla

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erika Curiel-GomezPosgrado en Ciencias Biológicas, Unidad de Posgrado, Edificio D, 1° Piso, Circuito de Posgrados, Ciudad Universitaria, Coyoacán, Mexico City C.P. 04510, Mexico.ORCID 0009-0004-9686-9065
Damaris P Romero-RodriguezLaboratorio Nacional Conahcyt de Investigación y Diagnóstico por Inmunocitofluorometría (LANCIDI), Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Calzada de Tlalpan 4502, Col. Belisario Domínguez Secc. 16, Tlalpan, Mexico City C.P. 14080, Mexico.
Mauricio Rodriguez-DorantesLaboratorio de Oncogenómica, Instituto Nacional de Medicina Genómica, Periférico Sur No. 4809, Col Arenal Tepepan, Tlalpan, Mexico City C.P. 14610, Mexico.ORCID 0000-0003-4249-7222
Vilma MaldonadoLaboratorio de Epigenética, Instituto Nacional de Medicina Genómica, Periférico Sur No. 4809, Col Arenal Tepepan, Tlalpan, Mexico City C.P. 14610, Mexico.ORCID 0000-0002-7254-5961
Jorge Melendez-ZajglaLaboratorio de Genómica Funcional del Cáncer, Instituto Nacional de Medicina Genómica, Periférico Sur No. 4809, Col Arenal Tepepan, Tlalpan, Mexico City C.P. 14610, Mexico.ORCID 0000-0002-2209-1607

Funding

SECIHTI CBF-2025-1-4446SECIHTI CVU.781517
6 · The paper itself

Abstract

The aggressiveness of pancreatic ductal adenocarcinoma (PDAC) has been linked to cancer stem cells (CSCs) and telomerase activity; however, the mechanism underlying this association remains unclear. In this study, we engineered dual transcriptional reporters (SORE6-GFP and TERT-BFP) to isolate SOX2

Indexed as

Neoplastic Stem CellsOctamer Transcription Factor-3Pancreatic NeoplasmsSOXB1 Transcription FactorsTelomeraseAnimalsCarcinoma, Pancreatic DuctalCell Line, TumorCell ProliferationEpithelial-Mesenchymal TransitionGene Expression Regulation, NeoplasticHumansOctamer Transcription Factor-3POU5F1 protein, humanSOX2 protein, humanSOXB1 Transcription FactorsTelomeraseTERT protein, humancancer stem cellspancreatic cancerSOX2-OCT4telomerase

Identifiers

PMID41597204
PMCPMC12839176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.