Evidence map›Paper›PMID 41596858›Full record

ArticleFoods (Basel, Switzerland)2026

Sustainable Anisaldehyde-Based Natural Deep Eutectic Solvent Dispersive Liquid-Liquid Microextraction for Monitoring Antibiotic Residues in Commercial Milk and Eggs: A Comprehensive Evaluation of Greenness, Practicality, Analytical Performance and Innovation.

Heba Shaaban, Ahmed Mostafa, Abdulmalik M Alqarni, Marwah Alsalman, Makarem A Alkhalaf, Mohammad A Alrofaidi, Abdulaziz H Al Khzem, Mansour S Alturki

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Heba ShaabanDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, King Faisal Road, Dammam 31441, Saudi Arabia.ORCID 0000-0001-5708-7686
Ahmed MostafaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, King Faisal Road, Dammam 31441, Saudi Arabia.ORCID 0000-0002-3350-8519
Abdulmalik M AlqarniDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, King Faisal Road, Dammam 31441, Saudi Arabia.ORCID 0000-0002-6955-0313
Marwah AlsalmanCollege of Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Makarem A AlkhalafCollege of Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Mohammad A AlrofaidiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Baha University, Al-Baha P.O. Box 1988, Saudi Arabia.
Abdulaziz H Al KhzemDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, King Faisal Road, Dammam 31441, Saudi Arabia.ORCID 0009-0004-0079-8646
Mansour S AlturkiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, King Faisal Road, Dammam 31441, Saudi Arabia.ORCID 0000-0001-7702-9379

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread use of antibiotics in human medicine, veterinary care, and livestock production has resulted in their frequent detection in diverse environmental and food matrices, making continuous surveillance of antibiotic residues in food products essential for consumer protection. In this study, a sustainable analytical method based on dispersive liquid-liquid microextraction (DLLME) coupled with UHPLC-MS/MS was developed for the trace determination of sulfamethoxazole, sulfadimethoxine, and enrofloxacin in commercial cow milk and chicken eggs. A natural deep eutectic solvent (NADES) composed of anisaldehyde and octanoic acid (2:1, molar ratio) was employed as a biodegradable extraction solvent, and key extraction parameters were systematically optimized. Under optimized conditions, the method demonstrated excellent linearity (R

Indexed as

antibioticsdispersive liquid-liquid microextractionDLLMEGACgreen analytical chemistrygreenness assessmentLC-MS/MSNADESnatural deep eutectic solventssustainable chemistry

Identifiers

PMID41596858
PMCPMC12840527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.