Evidence map›Paper›PMID 41596769›Full record

ArticleInternational journal of molecular sciences2026

Discovery and Preliminary Characterization of Lactose-Transforming Enzymes in

Katherine Rivero, Rodrigo Valenzuela, Inaira Rivero, Pedro General, Nicole Neira, Fernanda Contreras, Jans Alzate-Morales, Claudia Muñoz-Villagrán, Carlos Vera, Mauricio Arenas-Salinas and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Katherine RiveroLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0009-0002-2459-4360
Rodrigo ValenzuelaCentro de Bioinformática, Simulación y Modelado (CBSM), Facultad de Ingeniería, Universidad de Talca, Talca 3465548, Chile.
Inaira RiveroLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0009-0003-5963-1480
Pedro GeneralLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.
Nicole NeiraLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.
Fernanda ContrerasLaboratorio de Ecología de Ambientes Extremos, Centro de Genómica, Ecología y Medio Ambiente (GEMA), Universidad Mayor, Santiago 8580745, Chile.
Jans Alzate-MoralesCentro de Bioinformática, Simulación y Modelado (CBSM), Facultad de Ingeniería, Universidad de Talca, Talca 3465548, Chile.ORCID 0000-0001-9624-7849
Claudia Muñoz-VillagránLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0009-0009-8087-0287
Carlos VeraLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0000-0003-2179-9467
Mauricio Arenas-SalinasCentro de Bioinformática, Simulación y Modelado (CBSM), Facultad de Ingeniería, Universidad de Talca, Talca 3465548, Chile.
Felipe ArenasLaboratorio de Microbiología Molecular, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago 9170022, Chile.ORCID 0000-0001-5604-5919

Funding

FONDECYT 1230724
6 · The paper itself

Abstract

D-tagatose is a high-value, low-calorie sweetener that can be produced from dairy lactose via a two-step enzymatic route: lactose hydrolysis to galactose followed by galactose isomerization to tagatose. Here, we combined genomics, in silico structural analysis, and biochemical assays to evaluate the lactose-to-tagatose conversion potential of an Antarctic isolate, L47, identified as

Indexed as

Aldose-Ketose IsomerasesBacterial Proteinsbeta-GalactosidaseLactoseComputer SimulationEscherichia coliGalactoseGenomicsHexosesAldose-Ketose IsomerasesBacterial Proteinsbeta-GalactosidaseGalactoseHexosesLactoseL-arabinose isomerasetagatosebiocatalysisD-tagatoseinclusion bodieslactose valorizationL-arabinose isomeraseβ-galactosidase

Identifiers

PMID41596769
PMCPMC12842569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.