Evidence map›Paper›PMID 41596765›Full record

ArticleInternational journal of molecular sciences2026

Genome-Wide Identification Analysis of the MAPKKK Gene Family in Cotton and Its Role in Development and Stress Response.

Yahui Deng, Nan Zhao, Shuo Ning, Yifan Wang, Weiran Wang, Meng Wang, Zixin Zhou, Yaohua Li, Caixia Li, Lingfang Ran and 7 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yahui DengXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Nan ZhaoXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.ORCID 0000-0002-5218-1048
Shuo NingXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Yifan WangXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Weiran WangXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.ORCID 0009-0008-0868-700X
Meng WangXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Zixin ZhouXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Yaohua LiXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Caixia LiXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Lingfang RanXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Jiahui ZhuXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Zhiqing LiuXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Jing YangXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Alifu AierxiXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Jie KongXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.
Aixing GuCollege of Agronomy, Xinjiang Agricultural University, 311 Nongda East Road, Urumqi 830052, China.
Jianping LiXinjiang Key Laboratory of Cotton Genetic Improvement and Intelligent Production/National Cotton Engineering Technology Research Center, Cotton Research Institute of Xinjiang Uyghur Autonomous Region Academy of Agricultural Sciences, Urumqi 830091, China.

Funding

Nan Zhao (Gene mining and functional dissection of growth period in Sea Island cotton), the project of Xinjiang Research Institute of Agriculture in Arid Areas Hqny-2025002National Key R&D Program of China 2024YFD1200304Supported by the earmarked fund for Xinjiang Key Research and Development Program "R&D and Integrated Demonstration of Key Technologies and Equipment for Green Precision Prevention and Control of Cotton in Xinjiang 2024B02003-1the Project of Fund for Stable Support to Agricultural Sci-Tech Renovation xjnkywdzc-2026001-13-08 and xjnkywdzc-2026001-15the Project of Fund for the Xinjiang Uygur Autonomous Region Tianchi Talent-Young Doctor for Yahui Deng Study on the molecular mechanism of upland cotton's resistance to Verticillium wilt through phosphorylation modification of GhCPK1-GhMAPKKKI7-GhSD25 module
6 · The paper itself

Abstract

Mitogen-activated protein kinase kinase kinases (MAPKKKs) are pivotal upstream regulators of MAPK cascades, integrating signals that coordinate plant development and stress responses. However, the specific functions of MAPKKKs, particularly within the MEKK subfamily, in mediating cotton resistance to Verticillium wilt and Fusarium wilt remain poorly characterized. To address this, we conducted a systematic, cross-species analysis of the MAPKKK family in four key cotton species:

Indexed as

GossypiumMAP Kinase Kinase KinasesMultigene FamilyPlant ProteinsStress, PhysiologicalEvolution, MolecularGene Expression ProfilingGene Expression Regulation, PlantGenome, PlantPhylogenyMAP Kinase Kinase KinasesPlant Proteinsmitogen-activated protein kinase kinase kinasemodular functional diversificationsea island cottonstress defenseupland cotton

Identifiers

PMID41596765
PMCPMC12841829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.