Evidence map›Paper›PMID 41596745›Full record

ArticleInternational journal of molecular sciences2026

Effects and Molecular Mechanisms of Heat-Killed Postbiotic

Jin-Ho Lee, Kwon-Il Han, Eunwoo Jeong, Juyeong Moon, Min-Ah Kim, Bon Seo Koo, Yura Lee, Sunhwa Baek, Han Sung Kim, Tack-Joong Kim

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jin-Ho LeeDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.
Kwon-Il HanResearch & Development Center, bereum Co., Ltd., Wonju 26362, Republic of Korea.ORCID 0009-0003-5352-2822
Eunwoo JeongDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0009-0002-8144-6989
Juyeong MoonDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0009-0001-3400-4611
Min-Ah KimDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0000-0001-8113-2301
Bon Seo KooDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.
Yura LeeResearch & Development Center, bereum Co., Ltd., Wonju 26362, Republic of Korea.
Sunhwa BaekResearch & Development Center, bereum Co., Ltd., Wonju 26362, Republic of Korea.
Han Sung KimDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of Korea.
Tack-Joong KimDivision of Biological Science and Technology, Yonsei University, Wonju 26493, Republic of Korea.ORCID 0000-0002-1697-3232

Funding

the Ministry of SMEs and Startups (MSS, Republic of Korea) RS-2022-00167156
6 · The paper itself

Abstract

The interaction between the gut microbiota and human health has gained increasing recognition, accelerating advances in microbiome research. While early studies have emphasized probiotics, concerns regarding antibiotic resistance and adverse effects, such as sepsis, have shifted research interest towards heat-treated microbial cells or postbiotics. This study investigated the therapeutic potential of heat-killed postbiotic

Indexed as

DexamethasoneEnterococcus faecalisHand StrengthMuscular AtrophyProbioticsAnimalsCell LineHot TemperatureMaleMiceMuscle Fibers, SkeletalMuscle, SkeletalProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleySKP Cullin F-Box Protein LigasesDexamethasoneProto-Oncogene Proteins c-aktSKP Cullin F-Box Protein LigasesC2C12EF-2001Enterococcus faecalisgrip strengthmuscle atrophypostbiotic

Identifiers

PMID41596745
PMCPMC12842288

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.