Evidence map›Paper›PMID 41596730›Full record

ArticleInternational journal of molecular sciences2026

Loss of Epithelial Homeostasis Driven by TMBIM1 Depletion via E-Cadherin Junction Disassembly.

Zhenning Sun, Lei Zhang, Junxia Qi, Min Jiang, Shan Jiang, Zining Zhu, Yanxuan Ling, Xiaobin Wang, Juxue Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhenning SunSchool of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.
Lei ZhangJiangsu Provincial Key Laboratory of Molecular Targets and Intervention of Metabolic Disease, Nanjing Medical University, Nanjing 211166, China.
Junxia QiJiangsu Provincial Key Laboratory of Molecular Targets and Intervention of Metabolic Disease, Nanjing Medical University, Nanjing 211166, China.
Min JiangLaboratory Animal Centre, Southeast University, Nanjing 210096, China.
Shan JiangLaboratory Animal Centre, Southeast University, Nanjing 210096, China.
Zining ZhuJiangsu Provincial Key Laboratory of Molecular Targets and Intervention of Metabolic Disease, Nanjing Medical University, Nanjing 211166, China.
Yanxuan LingSchool of Medicine, Southeast University, Nanjing 210009, China.
Xiaobin WangLaboratory Animal Centre, Southeast University, Nanjing 210096, China.
Juxue LiSchool of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.ORCID 0000-0003-0681-5713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mounting evidence from large-scale association studies has identified transmembrane BAX inhibitor motif-containing 1 (

Indexed as

CadherinsColorectal NeoplasmsEpithelial CellsHomeostasisMembrane ProteinsCell ProliferationGene Expression Regulation, NeoplasticGene Knockdown TechniquesHCT116 CellsHumansCadherinsMembrane Proteinscell adhesionCOADE-cadherinMSITMBIM1

Identifiers

PMID41596730
PMCPMC12842013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.