Early Molecular Biomarkers in an Amyloid-β-Induced Rat Model of Alzheimer's Disease: Effects of Kelulut Honey.

Ammara Shaikh, Fairus Ahmad, Jayakumar Murthy, Seong Lin Teoh, Mohamad Fairuz Yahaya

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ammara ShaikhDepartment of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-8279-9917

Fairus AhmadDepartment of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-2452-6459

Jayakumar MurthyDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.

Seong Lin TeohDepartment of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-9733-8072

Mohamad Fairuz YahayaDepartment of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.

Funding

UKM Research University Grant GUP-2021-038

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the leading cause of dementia worldwide, characterized by progressive neurodegeneration and cognitive decline. Early diagnosis remains critical for enabling timely intervention. However, detecting the earliest pathological changes is challenging due to the limited availability of reliable biomarkers that reflect early disease pathology in experimental models. This study evaluated molecular markers associated with AD-related processes in a rat model inoculated with human amyloid β (Aβ)

Indexed as

Alzheimer DiseaseBiomarkersHoneyAmyloid beta-PeptidesAnimalsChemokine CCL2Disease Models, AnimalHippocampusMalePeptide FragmentsPhosphorylationRatsRats, Sprague-DawleySuperoxide Dismutase-1tau ProteinsTranscription Factor RelAAmyloid beta-Peptidesamyloid beta-protein (1-42)BiomarkersChemokine CCL2Peptide FragmentsSuperoxide Dismutase-1tau ProteinsTranscription Factor RelAAlzheimer’s diseaseELISAmolecular markersrat model

Identifiers

PMID41596702

DOI10.3390/ijms27021059

PMCPMC12842462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.