Evidence map›Paper›PMID 41596640›Full record

ArticleInternational journal of molecular sciences2026

Coxsackievirus B3 Cleaves INTS10 Through 3C Protease to Facilitate Its Replication.

Luna Yuan, Liling Lin, Chunyan Bi, Xiaoyu Niu, Yang Chen, Yanru Fei, Guangtian Wang, Hui Wang, Yan Wang, Wenran Zhao and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Luna YuanDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Liling LinDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.ORCID 0009-0001-0906-0523
Chunyan BiDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Xiaoyu NiuDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Yang ChenTeaching Center of Pathogenic Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Yanru FeiDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Guangtian WangTeaching Center of Pathogenic Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Hui WangTeaching Center of Pathogenic Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Yan WangDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Wenran ZhaoDepartment of Cell Biology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.
Zhaohua ZhongDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.ORCID 0000-0002-0778-5053
Lexun LinDepartment of Microbiology, School of Basic Medical Sciences, Harbin Medical University, Harbin 150081, China.ORCID 0000-0003-3404-2180

Funding

National Natural Science Foundation of China 82072278National Natural Science Foundation of China 82172247National Natural Science Foundation of China 82202493National Natural Science Foundation of China 82402598Natural Science Foundation of Heilongjiang Province grant LH2022H049
6 · The paper itself

Abstract

Coxsackieviruses possess two proteases that are engaged in cleaving viral polyprotein and hijacking host cell processes such as RNA biosynthesis. Integrator subunit 10 (INTS10), a subunit of the integrator complex, facilitates the processing of small nuclear RNAs (

Indexed as

Coxsackievirus InfectionsCysteine EndopeptidasesEnterovirus B, HumanViral ProteinsVirus Replication3C Viral ProteasesHeLa CellsHumansRNA, Small Nuclear3C Viral ProteasesCysteine EndopeptidasesRNA, Small NuclearViral ProteinsCoxsackievirus BINTS10snRNA processingvirus replication

Identifiers

PMID41596640
PMCPMC12841665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.