Evidence map›Paper›PMID 41596507›Full record

ArticleInternational journal of molecular sciences2026

Yifei Huang, Sean Yu, Qiang Cao, Weiqing Tang, Jia Jing, Bingzhong Xue, Hang Shi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yifei HuangDepartment of Biology, Georgia State University, Atlanta, GA 30303, USA.
Sean YuCentennial High School, Ellicott City, MD 21042, USA.
Qiang CaoDepartment of Biology, Georgia State University, Atlanta, GA 30303, USA.
Weiqing TangDivision of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Jia JingDepartment of Biology, Georgia State University, Atlanta, GA 30303, USA.
Bingzhong XueDepartment of Biology, Georgia State University, Atlanta, GA 30303, USA.ORCID 0000-0002-7857-1343
Hang ShiDepartment of Biology, Georgia State University, Atlanta, GA 30303, USA.

Funding

Crosstalk between sensory ghrelin signaling and adipose tissue sympathetic outflow regulates metabolic homeostasisR01DK125081 · NIDDK · GEORGIA STATE UNIVERSITY · PI XUE, BINGZHONG · 2020 to 2023
$2.3M
Epigenetic regulation of brown fat thermogenesis by the histone demethylase KDM6AR01DK118106 · NIDDK · GEORGIA STATE UNIVERSITY · PI SHI, HANG, XUE, BINGZHONG · 2019 to 2022
$1.7M
NIDDK NIH HHS R01 DK118106NIDDK NIH HHS R01 DK125081
6 · The paper itself

Abstract

Obesity arises from chronic energy imbalance, where energy intake exceeds energy expenditure. Emerging evidence supports a key role of DNA methylation in the regulation of adipose tissue development and metabolism. We have recently discovered a key role of DNA methylation, catalyzed by DNA methyltransferase 1 or 3a (

Indexed as

AdipocytesDNA (Cytosine-5-)-MethyltransferasesObesityStem CellsAdipose Tissue, BrownAnimalsDiet, High-FatDNA MethylationDNA Methyltransferase 3BEnergy MetabolismFemaleInsulin ResistanceMaleMiceMice, KnockoutThermogenesisDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BDNA methylationDnmt3bobesity

Identifiers

PMID41596507
PMCPMC12840943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.