Evidence map›Paper›PMID 41596334›Full record

ArticleInternational journal of molecular sciences2026

Integrated Plasma and Glial Cell Evidence Indicates a Functional Role for hsa-miR-342-5p in Spinocerebellar Ataxia Type 7 and Its Potential Use as a Biomarker.

Verónica M Borgonio-Cuadra, Aranza Meza-Dorantes, José Manuel Rodríguez-Pérez, Ian A García-Aguirre, Nadia Mireya Murillo-Melo, Nonanzit Pérez-Hernández, Oscar Hernández-Hernández, Marcela Hernández-Ortega, Zazil Herrera-Carrillo, Bulmaro Cisneros and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Verónica M Borgonio-CuadraLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Ciudad de México 14389, Mexico.
Aranza Meza-DorantesDepartment of Bioengineering, School of Engineering and Sciences, Tecnologico de Monterrey, Campus Ciudad de México, Ciudad de México 14380, Mexico.ORCID 0000-0003-4483-371X
José Manuel Rodríguez-PérezDepartamento de Biología Molecular, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México 14080, Mexico.ORCID 0000-0002-3802-0897
Ian A García-AguirreDepartment of Bioengineering, School of Engineering and Sciences, Tecnologico de Monterrey, Campus Ciudad de México, Ciudad de México 14380, Mexico.ORCID 0000-0002-3903-1467
Nadia Mireya Murillo-MeloLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Ciudad de México 14389, Mexico.
Nonanzit Pérez-HernándezDepartamento de Biología Molecular, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México 14080, Mexico.ORCID 0000-0003-4786-508X
Oscar Hernández-HernándezLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Ciudad de México 14389, Mexico.ORCID 0000-0001-6388-2459
Marcela Hernández-OrtegaEscuela Militar de Graduados de Sanidad, Secretaria de la Defensa Nacional, Miguel Hidalgo, Ciudad de México 11200, Mexico.ORCID 0000-0002-6758-4413
Zazil Herrera-CarrilloCentro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México, Huixquilucan 52786, Mexico.
Bulmaro CisnerosDepartment of Genetics and Molecular Biology, Center of Research and Advanced Studies (CINVESTAV-IPN), Ciudad de México 07360, Mexico.
Jonathan J MagañaLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Ciudad de México 14389, Mexico.ORCID 0000-0003-4399-4618

Funding

CONACYT SEP-2015-258043
6 · The paper itself

Abstract

Spinocerebellar ataxia type 7 (SCA7) is a neurodegenerative disease characterized by cerebellar ataxia and retinal degeneration, caused by an abnormal expansion of CAG repeats at the

Indexed as

MicroRNAsNeurogliaSpinocerebellar AtaxiasAdultAtaxin-7BiomarkersCell LineFemaleGene Expression RegulationHumansMaleMiddle AgedAtaxin-7ATXN7 protein, humanBiomarkersMicroRNAscirculating miRNAshuman glia cellsplasma biomarkerpolyQ diseasespinocerebellar ataxia type 7

Identifiers

PMID41596334
PMCPMC12840712

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.