Evidence map›Paper›PMID 41596317›Full record

ArticleInternational journal of molecular sciences2026

Stage-Specific Proteomic Adaptations to Heme-Induced Oxidative Stress in

Karla Barreto da Silva Orozimbo, Maria Aparecida Aride Bertonceli, Raquel de Souza Braga Silva, Rívea Cristina Custódio Rodrigues, Jucélia da Silva Araújo, Olga Lima Tavares Machado, Felipe Astolpho Almeida, Francisco José Alves Lemos

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karla Barreto da Silva OrozimboLaboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.ORCID 0009-0005-0582-2681
Maria Aparecida Aride BertonceliLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.ORCID 0000-0002-6501-4062
Raquel de Souza Braga SilvaLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.
Rívea Cristina Custódio RodriguesLaboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.
Jucélia da Silva AraújoLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.
Olga Lima Tavares MachadoLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.
Felipe Astolpho AlmeidaLaboratório de Química e Função de Proteínas e Peptídeos, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.ORCID 0000-0001-9415-1253
Francisco José Alves LemosLaboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Campos dos Goytacazes, Rio de Janeiro 28013-602, RJ, Brazil.ORCID 0000-0002-1435-4104

Funding

INCTEM/CNPq 465678/2014-9
6 · The paper itself

Abstract

Heme released during blood digestion represents a major oxidative challenge for hematophagous insects, promoting the generation of reactive oxygen species (ROS) and redox imbalance. Although

Indexed as

Adaptation, PhysiologicalAedesHemeOxidative StressProteomeProteomicsAnimalsFemaleInsect ProteinsLarvaMitochondriaOxidation-ReductionReactive Oxygen SpeciesHemeInsect ProteinsProteomeReactive Oxygen SpeciesAedes aegyptiheme toxicityoxidative stressproteomics

Identifiers

PMID41596317
PMCPMC12840970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.