Local Peritoneal Cytokine Response IL-1β, IL-6, TNF-α in a Standardized Neonatal Rat Model of Necrotizing Enterocolitis.

Tomasz Ciesielski, Marek Wolski, Łukasz Fus, Agnieszka Cudnoch-Jędrzejewska

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tomasz CiesielskiLaboratory of Centre for Preclinical Research, Chair and Department of Experimental and Clinical Physiology, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland.ORCID 0000-0003-1929-7767

Marek WolskiDepartment of Pediatric Surgery, Medical University of Warsaw, Zwirki i Wigury 63a, 02-091 Warsaw, Poland.ORCID 0000-0003-0550-1915

Łukasz FusDepartment of Pathology, Medical University of Warsaw, Pawinskiego 7, 02-106 Warsaw, Poland.

Agnieszka Cudnoch-JędrzejewskaLaboratory of Centre for Preclinical Research, Chair and Department of Experimental and Clinical Physiology, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland.

Funding

National Science Centre Preludium 18 grant. Grant nr: 2019/35/N/NZ5/02420

6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) is a life-threatening inflammatory disease of preterm infants, increasingly viewed as a cytokine-driven disorder of the immature intestine. We aimed to characterize local peritoneal concentrations of interleukin (IL)-1β, IL-6 and tumor necrosis factor-α (TNF-α) in a standardized neonatal rat NEC model and relate them to histopathological injury. Seventy-four SPRD/Mol/Lodz rat pups were allocated to a control group (CTRL;

Indexed as

Ascitic FluidCytokinesEnterocolitis, NecrotizingInterleukin-1betaInterleukin-6Tumor Necrosis Factor-alphaAnimalsAnimals, NewbornDisease Models, AnimalFemaleRatsCytokinesInterleukin-1betaInterleukin-6Tumor Necrosis Factor-alphacytokine profileinterleukin-1βinterleukin-6necrotizing enterocolitisneonatal rat modelperitoneal fluidtumor necrosis factor-α

Identifiers

PMID41596310

DOI10.3390/ijms27020658

PMCPMC12841518

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.