Evidence map›Paper›PMID 41596298›Full record

ArticleInternational journal of molecular sciences2026

Novel Homozygous Variants in CIDEC and WRN in a Young Female with Lipodystrophy and Thyroid Cancer.

Nivedita Patni, Chao Xing, Chun-Yuan Huang, Rebecca J Brown, Abhimanyu Garg

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nivedita PatniDivision of Endocrinology, Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-5926-7784
Chao XingMcDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-1838-0502
Chun-Yuan HuangMcDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Rebecca J BrownNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-2589-7382
Abhimanyu GargThe Section of Nutrition and Metabolic Diseases, Division of Endocrinology, Department of Internal Medicine and the Center for Human Nutrition, UT Southwestern Medical Center, Dallas, TX 75390, USA.

Funding

UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeff G McDonald · 2022 to 2026
$7.4M
NIDDK NIH HHS P30 DK127984NIH HHS R01-DK105448
6 · The paper itself

Abstract

Autosomal recessive familial partial lipodystrophy type 5 (FPLD5) due to a homozygous NP_001186481.1; p.E186*

Indexed as

Lipodystrophy, Familial PartialThyroid NeoplasmsAdolescentFemaleHomozygoteHumansMutationThyroid Cancer, PapillaryCIDECFSP27papillary thyroid carcinomapartial lipodystrophyWRN

Identifiers

PMID41596298
PMCPMC12840685

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.