ArticleAntioxidants (Basel, Switzerland)2026
Angiotensin-Converting Enzyme (ACE) Inhibitors and Statins Mitigate Negative Cardiovascular and Pulmonary Effects of Particulate Matter in a Mouse Exposure Model.
Tristan Junglas, Andreas Daiber, Ivana Kuntic, Arijan Valar, Jiayin Zheng, Matthias Oelze, Lea Strohm, Henning Ubbens, Omar Hahad, Maria Teresa Bayo Jimenez and 2 more
Abstract read
In one paragraphArticle in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Tristan JunglasMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.
Andreas DaiberMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-2769-0094 Ivana KunticMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0003-3862-185X Arijan ValarMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0009-0003-5997-0263 Jiayin ZhengMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0009-0002-6471-3248 Matthias OelzeMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-5939-7263 Lea StrohmMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.
Henning UbbensMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0009-0007-1725-4903 Omar HahadMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7823-7671 Maria Teresa Bayo JimenezMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7159-8992 Thomas MünzelMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-5503-4150 Marin KunticMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0003-2435-851X Funding
Boehringer Ingelheim Foundation Novel and neglected cardiovascular risk factors: molecular mechanisms and therapeuticsEXPOHEALTH, Rhineland-Palatinate, GermanyFoundation Heart of MainzWahl-Stumpf Foundation
6 · The paper itselfAbstract
Particulate matter (PM) is a significant contributor to air pollution-associated negative health effects, and cardiovascular disease patients are more susceptible to air pollution-mediated damage of the heart and vessels. The present study investigated the protective effects against PM-induced cardiovascular damage by classic cardiovascular drugs, as used for the standard therapy of cardiovascular disease patients. Male C57BL/6J mice were exposed to ambient PM
Indexed as
angiotensin-converting enzyme (ACE)-inhibitorsendothelial dysfunctionoxidative stressparticulate matterstatins
Identifiers
PMID41596164
PMCPMC12837575
What OpenQuestion holds
Textmetadata
LicenceCC BY
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