Evidence map›Paper›PMID 41596164›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Angiotensin-Converting Enzyme (ACE) Inhibitors and Statins Mitigate Negative Cardiovascular and Pulmonary Effects of Particulate Matter in a Mouse Exposure Model.

Tristan Junglas, Andreas Daiber, Ivana Kuntic, Arijan Valar, Jiayin Zheng, Matthias Oelze, Lea Strohm, Henning Ubbens, Omar Hahad, Maria Teresa Bayo Jimenez and 2 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tristan JunglasMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.
Andreas DaiberMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-2769-0094
Ivana KunticMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0003-3862-185X
Arijan ValarMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0009-0003-5997-0263
Jiayin ZhengMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0009-0002-6471-3248
Matthias OelzeMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-5939-7263
Lea StrohmMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.
Henning UbbensMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0009-0007-1725-4903
Omar HahadMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7823-7671
Maria Teresa Bayo JimenezMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7159-8992
Thomas MünzelMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-5503-4150
Marin KunticMolecular Cardiology, Department for Cardiology 1, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0003-2435-851X

Funding

Boehringer Ingelheim Foundation Novel and neglected cardiovascular risk factors: molecular mechanisms and therapeuticsEXPOHEALTH, Rhineland-Palatinate, GermanyFoundation Heart of MainzWahl-Stumpf Foundation
6 · The paper itself

Abstract

Particulate matter (PM) is a significant contributor to air pollution-associated negative health effects, and cardiovascular disease patients are more susceptible to air pollution-mediated damage of the heart and vessels. The present study investigated the protective effects against PM-induced cardiovascular damage by classic cardiovascular drugs, as used for the standard therapy of cardiovascular disease patients. Male C57BL/6J mice were exposed to ambient PM

Indexed as

angiotensin-converting enzyme (ACE)-inhibitorsendothelial dysfunctionoxidative stressparticulate matterstatins

Identifiers

PMID41596164
PMCPMC12837575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.