A Neutral Polysaccharide from Ginseng Berry Mitigates D-Galactose-Induced Oxidative Stress and Cognitive Deficits Through the Keap1/Nrf2/HO-1/NQO1 Pathway.

Ting Ren, Lina Wang, Jiaxin Zhang, Ruitong Song, Xin Li, Jiayue Gao, Xin Sun, Lili Jiao

Abstract read

In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Ting RenSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Lina WangSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Jiaxin ZhangSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Ruitong SongSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Xin LiSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Jiayue GaoSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Xin SunSchool of Pharmaceutical Sciences, Jilin Medical University, Jilin 132013, China.

Lili JiaoJilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China.

Funding

the Doctoral Fund of Jilin Medical University JYBS2023009LKthe Jilin Province Health Science and Technology Capacity Improvement Project 2025WS-KA030

6 · The paper itself

Abstract

Oxidative stress contributes to brain aging processes and is implicated in related functional decline. Developing strategies to mitigate oxidative stress is therefore of significant interest. In this study, a neutral polysaccharide (GBPN) was isolated from ginseng berry. Structural analysis revealed that GBPN (molecular weight 1.52 × 10

Indexed as

cognitive deficitsD-galactose-induced aging-like miceginseng berry polysaccharideoxidative stressstructural characteristics

Identifiers

PMID41596123

DOI10.3390/antiox15010065

PMCPMC12837864

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