ArticleBioengineering (Basel, Switzerland)2026
A Novel Murine Model to Study the Early Biological Events of Corticosteroid-Associated Osteonecrosis of the Femoral Head.
Issei Shinohara, Yosuke Susuki, Simon Kwoon-Ho Chow, Pierre Cheung, Abraham S Moses, Masatoshi Murayama, Mayu Morita, Tomohiro Uno, Qi Gao, Chao Ma and 3 more
Abstract read
In one paragraphArticle in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Issei ShinoharaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-4122-7119 Yosuke SusukiDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.
Simon Kwoon-Ho ChowDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0003-1742-980X Pierre CheungDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-1330-9800 Abraham S MosesDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Masatoshi MurayamaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0009-0000-1228-482X Mayu MoritaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.
Tomohiro UnoDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-3389-5272 Qi GaoDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0003-0175-566X Chao MaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-1049-6172 Takahiro IgeiDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.
Corinne BeinatDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stuart B GoodmanDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-1919-3717 Funding
The Robert L. and Mary Ellenberg Chair in Surgery, Stanford University NA
6 · The paper itselfAbstract
This study establishes a murine model of corticosteroid-associated osteonecrosis of the femoral head (ONFH) using a sustained-release prednisolone pellet and evaluates mitochondrial stress using
Indexed as
corticosteroidosteonecrosisoxidative stressPET/CTreactive oxygen species
Identifiers
PMID41596047
PMCPMC12837465
What OpenQuestion holds
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