Evidence map›Paper›PMID 41596047›Full record

ArticleBioengineering (Basel, Switzerland)2026

A Novel Murine Model to Study the Early Biological Events of Corticosteroid-Associated Osteonecrosis of the Femoral Head.

Issei Shinohara, Yosuke Susuki, Simon Kwoon-Ho Chow, Pierre Cheung, Abraham S Moses, Masatoshi Murayama, Mayu Morita, Tomohiro Uno, Qi Gao, Chao Ma and 3 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Issei ShinoharaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-4122-7119
Yosuke SusukiDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.
Simon Kwoon-Ho ChowDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0003-1742-980X
Pierre CheungDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-1330-9800
Abraham S MosesDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Masatoshi MurayamaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0009-0000-1228-482X
Mayu MoritaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.
Tomohiro UnoDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-3389-5272
Qi GaoDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0003-0175-566X
Chao MaDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-1049-6172
Takahiro IgeiDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.
Corinne BeinatDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stuart B GoodmanDepartment of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA 94063, USA.ORCID 0000-0002-1919-3717

Funding

The Robert L. and Mary Ellenberg Chair in Surgery, Stanford University NA
6 · The paper itself

Abstract

This study establishes a murine model of corticosteroid-associated osteonecrosis of the femoral head (ONFH) using a sustained-release prednisolone pellet and evaluates mitochondrial stress using

Indexed as

corticosteroidosteonecrosisoxidative stressPET/CTreactive oxygen species

Identifiers

PMID41596047
PMCPMC12837465

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.