Evidence map›Paper›PMID 41596039›Full record

ReviewBioengineering (Basel, Switzerland)2026

Artificial Authority: The Promise and Perils of LLM Judges in Healthcare.

Ariana Genovese, Lars Hegstrom, Srinivasagam Prabha, Cesar A Gomez-Cabello, Syed Ali Haider, Bernardo Collaco, Nadia G Wood, Antonio Jorge Forte

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Artificial Intelligence Across the Drug Development Lifecycle.Medical sciences (Basel, Switzerland) · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ariana GenoveseDivision of Plastic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0009-0000-9678-2163
Lars HegstromCenter for Digital Health, Mayo Clinic, Rochester, MN 55905, USA.
Srinivasagam PrabhaDivision of Plastic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.
Cesar A Gomez-CabelloDivision of Plastic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0009-0008-0603-3192
Syed Ali HaiderDivision of Plastic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0009-0007-5621-2861
Bernardo CollacoDivision of Plastic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0000-0003-3845-2646
Nadia G WoodDepartment of Radiology AI IT, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-2685-6427
Antonio Jorge ForteDivision of Plastic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.ORCID 0000-0003-2004-7538

Funding

CSRD VA 1Dalio Philanthropies 2Gerstner Philanthropies 3
6 · The paper itself

Abstract

backgroundLarge language models (LLMs) are increasingly integrated into clinical documentation, decision support, and patient-facing applications across healthcare, including plastic and reconstructive surgery. Yet, their evaluation remains bottlenecked by costly, time-consuming human review. This has given rise to LLM-as-a-judge, in which LLMs are used to evaluate the outputs of other AI systems.

methodsThis review examines LLM-as-a-judge in healthcare with particular attention to judging architectures, validation strategies, and emerging applications. A narrative review of the literature was conducted, synthesizing LLM judge methodologies as well as judging paradigms, including those applied to clinical documentation, medical question-answering systems, and clinical conversation assessment.

resultsAcross tasks, LLM judges align most closely with clinicians on objective criteria (e.g., factuality, grammaticality, internal consistency), benefit from structured evaluation and chain-of-thought prompting, and can approach or exceed inter-clinician agreement, but remain limited for subjective or affective judgments and by dataset quality and task specificity.

conclusionsThe literature indicates that LLM judges can enable efficient, standardized evaluation in controlled settings; however, their appropriate role remains supportive rather than substitutive, and their performance may not generalize to complex plastic surgery environments. Their safe use depends on rigorous human oversight and explicit governance structures.

Indexed as

artificial intelligencebenchmarkingclinical decision support systemscomputer assisteddecision makinglarge language modelLLM-as-a-judge

Identifiers

PMID41596039
PMCPMC12837895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.