Evidence map›Paper›PMID 41596037›Full record

ReviewBioengineering (Basel, Switzerland)2026

Jawbone Cavitations: Current Understanding and Conceptual Introduction of Covered Socket Residuum (CSR).

Shahram Ghanaati, Anja Heselich, Johann Lechner, Robert Sader, Jerry E Bouquot, Sarah Al-Maawi

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shahram GhanaatiDepartment of Oral, Cranio-Maxillofacial and Facial Plastic Surgery, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0002-7897-0854
Anja HeselichDepartment of Oral, Cranio-Maxillofacial and Facial Plastic Surgery, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.ORCID 0000-0002-6799-8325
Johann LechnerClinic for Integrative Dentistry, 81547 Munich, Germany.ORCID 0000-0001-9800-0276
Robert SaderDepartment of Oral, Cranio-Maxillofacial and Facial Plastic Surgery, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.
Jerry E BouquotDepartment of Oral & Maxillofacial Surgery, West Virginia University, Morgantown, WV 26506-9400, USA.ORCID 0000-0003-0715-788X
Sarah Al-MaawiDepartment of Oral, Cranio-Maxillofacial and Facial Plastic Surgery, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany.

Funding

Academy for Biological Innovations (ABIS) e.V., Frankfurt/Main, Germany N/A
6 · The paper itself

Abstract

Jawbone cavitations have been described for decades under various terminologies, including neuralgia-inducing cavitational osteonecrosis (NICO) and fatty degenerative osteolysis of the jawbone (FDOJ). Their biological nature and clinical relevance remain controversial. The present review aimed to summarize the current understanding of jawbone cavitations, identify relevant research gaps, and propose a unified descriptive terminology. This narrative literature review was conducted using PubMed/MEDLINE, Google Scholar, and manual searches of relevant journals. The available evidence was qualitatively synthesized. The results indicate that most published data on jawbone cavitations are derived from observational, retrospective, and cohort studies, with etiological concepts largely based on histopathological findings. Recent three-dimensional radiological analyses suggest that intraosseous non-mineralized areas frequently observed at former extraction sites may represent a physiological outcome of socket collapse and incomplete ossification rather than a pathological condition. This review introduces Covered Socket Residuum (CSR) as a radiological descriptive term and clearly distinguishes it from pathological entities such as NICO and FDOJ. Recognition of CSR is clinically relevant, particularly in dental implant planning, where unrecognized non-mineralized areas may compromise primary stability. The findings emphasize the role of three-dimensional radiological assessment for diagnosis and implant planning and discuss preventive and therapeutic strategies, including Guided Open Wound Healing (GOWH

Indexed as

bone regenerationcavitationCovered Socket Residuum (CSR)critical size defectFatty Degenerative Osteolysis of the Jawbone (FDOJ)Guided Open Wound Healing (GOWH)Neuralgia-Inducing Cavitational Osteonecrosis (NICO)Platelet-Rich Fibrin (PRF)post-extraction healing

Identifiers

PMID41596037
PMCPMC12838184

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.