Evidence map›Paper›PMID 41596002›Full record

ArticleBioengineering (Basel, Switzerland)2026

Functional Electrical Stimulation (FES) in Adults with Neurological Disorders and Foot Drop: Orthotic and Therapeutic Effects in Short- and Long-Term Users.

Niklas Bleichner, Merkur Alimusaj, Daniel W W Heitzmann, Andreas Stähle, Claudia Weichold, Cornelia Putz, Herta Flor, Frauke Nees, Sebastian I Wolf

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Niklas BleichnerClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.ORCID 0009-0009-9236-0487
Merkur AlimusajClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.
Daniel W W HeitzmannClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.ORCID 0000-0001-8121-1923
Andreas StähleClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.
Claudia WeicholdClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.
Cornelia PutzClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.
Herta FlorResearch Group Learning and Brain Plasticity in Mental Disorders, Department of Neuropsychology and Psychological Resilience Research, Central Institute of Mental Health, Medical Faculty Heidelberg University, 68159 Mannheim, Germany.ORCID 0000-0003-4809-5398
Frauke NeesInstitute of Medical Psychology, Ludwig-Maximilians-Universität (LMU Munich), 80336 Munich, Germany.
Sebastian I WolfClinic for Orthopedics, Heidelberg University Hospital, 69118 Heidelberg, Germany.ORCID 0000-0003-3921-6629

Funding

Deutsche Forschungsgemeinschaft (DFG) GRK 2761
6 · The paper itself

Abstract

Functional electrical stimulation (FES) is widely used to improve gait in individuals with neurological impairments; however, early responses in adults with congenital conditions, such as cerebral palsy, who are newly exposed to FES, remain poorly understood. This study investigated the orthotic and therapeutic effects of FES in short- and long-term users using standardized three-dimensional gait analysis. In this longitudinal study, short-term users (G1; n = 13; mean age 31.7 ± 18.1 years) were evaluated both without and with FES and followed over a 4-12-week insurance-covered trial period. Long-term users (G2; n = 11; mean age 32.2 ± 11.0 years), who had used FES for at least one year, were reassessed over a standardized 12-week interval. Linear mixed-effects models assessed the effects of FES and time, with subjects included as random effects to account for inter-individual variability. G1 showed significant therapeutic adaptations, including increased walking speed and step length and reduced step width, accompanied by decreased dorsiflexion during stance and swing, while no significant orthotic effects were observed. G2 demonstrated clear orthotic responses, such as increased dorsiflexion at heel strike and during swing and improved walking speed and step length, with minimal evidence of additional therapeutic adaptation. The initial reduction in dorsiflexion in G1 warrants further investigation. These findings suggest that evaluation timelines may need to be extended and that outcome measures beyond foot clearance should be considered, particularly given the heterogeneity and severity of congenital neurological conditions.

Indexed as

foot dropfunctional electrical stimulationgaitkinematicsneurological disordersrehabilitationspatio-temporal parameters

Identifiers

PMID41596002
PMCPMC12838254

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.